Background: Numerous physical, psychological, and emotional benefits have been
attributed to marijuana since its first reported use in 2,600 BC in a Chinese pharmacopoeia …

Recent advances in understanding of the mode of action of tetrahydrocannabinol and
related cannabinoid in-gredients of marijuana, plus the accumulating anecdotal reports on …

The role of cannabis in medicine is rapidly evolving. Medical cannabis is now legal in a
majority of states, and THC and CBD, the prominent cannabinoids found in cannabis, have …

After thousands of years of interest the last few decades have seen a huge increase in our
knowledge of the cannabinoids and their mode of action. Their potential as medical …

The Cannabis plant has been used for many of years as a medicinal agent in the relief of
pain and seizures. It contains approximately 540 natural compounds including more than …

Charlotte, a little girl with SCN 1 A‐confirmed D ravet syndrome, was recently featured in a
special that aired on CNN. Through exhaustive personal research and assistance from a C …

γ-Aminobutyric acid type A receptors (GABAARs) are the main inhibitory mediators in the
central nervous system (CNS). GABAARs are pentameric ligand gated ion channels, and the …

Cannabis sativa L. preparations have been used in medicine for millenia. However, concern
over the dangers of abuse led to the banning of the medicinal use of marijuana in most …

The major psychoactive constituent of Cannabis sativa, Δ 9-tetrahydrocannabinol (Δ 9-THC),
and endogenous cannabinoid ligands, such as anandamide, signal through G-protein …

Cannabinoids form a singular family of plant-derived compounds (phytocannabinoids),
endogenous signaling lipids (endocannabinoids), and synthetic derivatives with multiple …