Photobiomodulation in diabetic wound healing: a review of red and near‐infrared wavelength applications

O Oyebode, NN Houreld… - Cell Biochemistry and …, 2021 - Wiley Online Library
The development of a painless, non‐invasive, and faster way to diabetic wound healing is at
the forefront of research. The complexity associated with diabetic wounds makes it a cause …

Healing effects of photobiomodulation on diabetic wounds

N Houreld - Applied Sciences, 2019 - mdpi.com
Diabetic patients frequently develop chronic ulcers of the lower extremities, which are a
frequent cause for hospitalization and amputation, placing strain on patients, their families …

Photobiomodulation at 660 nm stimulates in vitro diabetic wound healing via the Ras/MAPK pathway

P Kasowanjete, H Abrahamse, NN Houreld - Cells, 2023 - mdpi.com
Diabetic foot ulcers (DFUs) are open chronic wounds that affect diabetic patients due to
hyperglycaemia. DFUs are known for their poor response to treatment and frequently require …

Optimization of photo-biomodulation therapy for wound healing of diabetic foot ulcers in vitro and in vivo

Q Chen, J Yang, H Yin, Y Li, H Qiu, Y Gu… - Biomedical Optics …, 2022 - opg.optica.org
Unclear optical parameters make photo-biomodulation (PBM) difficult to implement in
diabetic foot ulcer (DFU) clinically. Here, 12 wavelengths (400–900 nm) were used to …

Cell adhesion molecules are mediated by photobiomodulation at 660 nm in diabetic wounded fibroblast cells

NN Houreld, SM Ayuk, H Abrahamse - Cells, 2018 - mdpi.com
Diabetes affects extracellular matrix (ECM) metabolism, contributing to delayed wound
healing and lower limb amputation. Application of light (photobiomodulation, PBM) has been …

Noninvasive red and near‐infrared wavelength‐induced photobiomodulation: promoting impaired cutaneous wound healing

A Yadav, A Gupta - Photodermatology, photoimmunology & …, 2017 - Wiley Online Library
The innumerable intricacies associated with chronic wounds have made the development of
new painless, noninvasive, biophysical therapeutic interventions as the focus of current …

[HTML][HTML] Photobiomodulation activates the PI3K/AKT pathway in diabetic fibroblast cells in vitro

SW Jere, NN Houreld, H Abrahamse - Journal of Photochemistry and …, 2022 - Elsevier
Photobiomodulation (PBM) has been known to facilitate the healing of numerous ailments
including diabetic wounds. PBM is not broadly acknowledged largely due to skepticism …

[HTML][HTML] Photobiomodulation at 660 nm stimulates proliferation and migration of diabetic wounded cells via the expression of epidermal growth factor and the JAK …

SW Jere, NN Houreld, H Abrahamse - Journal of Photochemistry and …, 2018 - Elsevier
Photobiomodulation (PBM) modulates cellular processes to enhance diabetic wound
healing. The photon energy activates wounded cells to proliferate and migrate. However, the …

Improved wound remodeling correlates with modulated TGF‐beta expression in skin diabetic wounds following combined red and infrared photobiomodulation …

R Fekrazad, A Sarrafzadeh, KAM Kalhori… - Photochemistry and …, 2018 - Wiley Online Library
Diabetic wounds are a major cause of morbidity among patients with poorly controlled blood
glucose levels. Conventional empirical wound care strategies have shown limited efficacy …

[HTML][HTML] Photobiomodulation therapy improves the growth factor and cytokine secretory profile in human type 2 diabetic fibroblasts

ER Layegh, FF Fathabadi, M Lotfinia, F Zare… - … of Photochemistry and …, 2020 - Elsevier
Impaired wound healing is a common complication of diabetes mellitus (DM) and the
underlying mechanism of this impairment is still unclear. Fibroblast, as the main …