Nicorandil exerts myocardial protection through its antihypoxia and antioxidant effects. Here,
we investigated whether it plays an anti‐apoptotic role in diabetic cardiomyopathy. Sprague …

Background/Aims: As a vasodilatory drug used to treat angina, nicorandil has been shown to
induce an infarct-limiting effect in various experimental animal models of myocardial …

Nicorandil has been shown to inhibit myocyte apoptosis by opening of mitochondrial ATP-
sensitive potassium (mitoKATP) channels and nitrate-like effect against oxidative stress …

Pyroptosis is an inflammatory cell death that regulates cardiomyocyte loss after myocardial
infarction. Reports indicate that nicorandil has a strong anti-inflammatory effect and protects …

Abstract Recently, naringin (NAR; 4', 5, 7-trihydroxyflavanone-7-rhamnoglucoside) has been
shown to have cardioprotective properties. However, the specific mechanisms underlying its …

Baicalein Protects Rats with Diabetic Cardiomyopathy Against Oxidative Stress and
Inflammation Injury via Phosphatidylinositol 3-Kinase (PI3K)/AKT Pathway - PMC Back to Top …

Diabetic cardiomyopathy, which refers to the destruction of the structure and function of the
heart, is the primary cause of heart failure due to diabetes. LCZ696 is the first angiotensin …

Diabetic cardiomyopathy (DCM) is a chronic microvascular complication of diabetes that is
generally defined as ventricular dysfunction occurring in patients with diabetes and …

Diabetes is a disorder of glucose metabolism, and over 90% are type 2 diabetes. Diabetic
cardiomyopathy (DCM) is one of the type 2 diabetes complications, usually accompanied by …

The function of curcumin on NADPH oxidase‐related ROS production and cardiac
apoptosis, together with the modulation of protein signalling pathways, was investigated in …