Neonatal hind-paw injury disrupts acquisition of an instrumental response in adult spinal rats.
EE Young, KM Baumbauer, A Elliot… - Behavioral …, 2007 - psycnet.apa.org
The present study was designed to evaluate the impact of neonatal injury on adult spinal
plasticity in rats. Subjects were randomly assigned to 1 of 4 experimental conditions:(a) hind …
plasticity in rats. Subjects were randomly assigned to 1 of 4 experimental conditions:(a) hind …
Local anesthetic treatment significantly attenuates acute pain responding but does not prevent the neonatal injury-induced reduction in adult spinal behavioral …
EE Young, KM Baumbauer, J Hillyer… - Behavioral …, 2007 - psycnet.apa.org
Recent findings indicate that neonatal injury results in decreased spinal plasticity in adult
subjects (EE Young, KM Baumbauer, AE Elliot, & RL Joynes, 2007). Previous research has …
subjects (EE Young, KM Baumbauer, AE Elliot, & RL Joynes, 2007). Previous research has …
The neonatal injury-induced spinal learning deficit in adult rats: central mechanisms.
EE Young, KM Baumbauer, JE Hillyer… - Behavioral …, 2008 - psycnet.apa.org
Previous research has shown that small injuries early in development can alter adult pain
reactivity and processing of stimuli presented to the side of injury. However, the mechanisms …
reactivity and processing of stimuli presented to the side of injury. However, the mechanisms …
Instrumental learning within the spinal cord: underlying mechanisms and implications for recovery after injury
Using spinally transected rats, research has shown that neurons within the L4-S2 spinal
cord are sensitive to response-outcome (instrumental) relations. This learning depends on a …
cord are sensitive to response-outcome (instrumental) relations. This learning depends on a …
Developmental tuning in a spinal nociceptive system: effects of neonatal spinalization
A Levinsson, XL Luo, H Holmberg… - Journal of …, 1999 - Soc Neuroscience
Recent studies indicate a modular organization of the nociceptive withdrawal reflex system.
Each module has a characteristic receptive field, closely matching the withdrawal movement …
Each module has a characteristic receptive field, closely matching the withdrawal movement …
Instrumental learning within the spinal cord: V. Evidence the behavioral deficit observed after noncontingent nociceptive stimulation reflects an intraspinal modification
RL Joynes, AR Ferguson, ED Crown, BC Patton… - Behavioural brain …, 2003 - Elsevier
Spinally transected rats given leg shock whenever one hindlimb is extended learn to
maintain the leg in a flexed position, which minimizes net shock exposure. Yoked rats, that …
maintain the leg in a flexed position, which minimizes net shock exposure. Yoked rats, that …
Instrumental learning within the spinal cord: II. Evidence for central mediation
Rats spinally transected at the second thoracic vertebra can learn to maintain their leg in a
flexed position if they receive legshock for extending the limb. These rats display an …
flexed position if they receive legshock for extending the limb. These rats display an …
Timing in the absence of supraspinal input I: variable, but not fixed, spaced stimulation of the sciatic nerve undermines spinally-mediated instrumental learning
Rats with complete spinal transections are capable of acquiring a simple instrumentally
trained response. If rats receive shock to one hind limb when the limb is extended …
trained response. If rats receive shock to one hind limb when the limb is extended …
Instrumental learning within the rat spinal cord: localization of the essential neural circuit.
GT Liu, AR Ferguson, ED Crown, AC Bopp… - Behavioral …, 2005 - psycnet.apa.org
Following spinal transection of the upper thoracic spinal cord, male Sprague–Dawley rats
given legshock whenever a hindlimb is extended learn to maintain the leg in a flexed …
given legshock whenever a hindlimb is extended learn to maintain the leg in a flexed …
Instrumental learning within the spinal cord: I. Behavioral properties.
JW Grau, DG Barstow, RL Joynes - Behavioral neuroscience, 1998 - psycnet.apa.org
Four experiments are reported that explore whether spinal neurons can support instrumental
learning. During training, one group of spinal rats (master) received legshock whenever one …
learning. During training, one group of spinal rats (master) received legshock whenever one …