Mitochondrial dysfunction is a key pathway that links saturated fat intake to the development and progression of NAFLD

RCR Meex, EE Blaak - Molecular nutrition & food research, 2021 - Wiley Online Library
Non‐Alcoholic fatty liver disease (NAFLD) is the most common form of liver disease and is
characterized by fat accumulation in the liver. Hypercaloric diets generally increase hepatic …

[HTML][HTML] Nonalcoholic fatty liver disease and mitochondrial dysfunction

Y Wei, RS Rector, JP Thyfault… - World journal of …, 2008 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) includes hepatic steatosis, nonalcoholic
steatohepatitis (NASH), fibrosis, and cirrhosis. NAFLD is the most common liver disorder in …

[HTML][HTML] Western diet causes obesity-induced nonalcoholic fatty liver disease development by differentially compromising the autophagic response

ICM Simoes, A Karkucinska-Wieckowska, J Janikiewicz… - Antioxidants, 2020 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is characterized by the development of steatosis,
which can ultimately compromise liver function. Mitochondria are key players in obesity …

[PDF][PDF] Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease

K Begriche, J Massart, MA Robin, F Bonnet… - …, 2013 - Wiley Online Library
The worldwide epidemic of obesity and insulin resistance favors nonalcoholic fatty liver
disease (NAFLD). Insulin resistance (IR) in the adipose tissue increases lipolysis and the …

[HTML][HTML] Role of mitochondria in nonalcoholic fatty liver disease

F Nassir, JA Ibdah - International journal of molecular sciences, 2014 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) affects about 30% of the general population in the
United States and includes a spectrum of disease that includes simple steatosis, non …

Changes in key mitochondrial lipids accompany mitochondrial dysfunction and oxidative stress in NAFLD

M Durand, M Coué, M Croyal, T Moyon… - Oxidative medicine …, 2021 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a dysmetabolic hepatic damage of increasing
severity: simple fat accumulation (steatosis), nonalcoholic steatohepatitis (NASH), and …

[HTML][HTML] The impact of macronutrient intake on non-alcoholic fatty liver disease (NAFLD): too much fat, too much carbohydrate, or just too many calories?

T Hydes, U Alam, DJ Cuthbertson - Frontiers in nutrition, 2021 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is a growing epidemic, in parallel with the obesity
crisis, rapidly becoming one of the commonest causes of chronic liver disease worldwide …

Differential alterations in mitochondrial function induced by a choline-deficient diet: understanding fatty liver disease progression

JS Teodoro, AP Rolo, FV Duarte, AM Simões… - Mitochondrion, 2008 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is an increasingly reported pathology,
characterized by fat accumulation within the hepatocyte. Growing evidences suggest …

[HTML][HTML] Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis

T Schröder, D Kucharczyk, F Bär, R Pagel, S Derer… - Molecular …, 2016 - Elsevier
Objective Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver
disease and is associated with an enhanced risk for liver and cardiovascular diseases and …

High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo

SK Mantena, DP Vaughn Jr, KK Andringa… - Biochemical …, 2009 - portlandpress.com
NAFLD (non-alcoholic fatty liver disease), associated with obesity and the cardiometabolic
syndrome, is an important medical problem affecting up to 20% of western populations …