[HTML][HTML] Nanoparticle-based drug delivery in cancer therapy and its role in overcoming drug resistance

Y Yao, Y Zhou, L Liu, Y Xu, Q Chen, Y Wang… - Frontiers in molecular …, 2020 - frontiersin.org
Nanotechnology has been extensively studied and exploited for cancer treatment as
nanoparticles can play a significant role as a drug delivery system. Compared to …

[HTML][HTML] Nanoparticles for cancer therapy: current progress and challenges

S Gavas, S Quazi, TM Karpiński - Nanoscale research letters, 2021 - Springer
Cancer is one of the leading causes of death and morbidity with a complex pathophysiology.
Traditional cancer therapies include chemotherapy, radiation therapy, targeted therapy, and …

Cancer chemotherapy resistance: Mechanisms and recent breakthrough in targeted drug delivery

F Davodabadi, SF Sajjadi, M Sarhadi… - European Journal of …, 2023 - Elsevier
Conventional chemotherapy, one of the most widely used cancer treatment methods, has
serious side effects, and usually results in cancer treatment failure. Drug resistance is one of …

Nanoparticle therapeutics: Technologies and methods for overcoming cancer

BBS Cerqueira, A Lasham, AN Shelling… - European Journal of …, 2015 - Elsevier
It is anticipated that by 2030 approximately 13 million people will die of cancer. Common
cancer therapy often fails due to the development of multidrug resistance (MDR), resulting in …

[HTML][HTML] Perspectives of nano-carrier drug delivery systems to overcome cancer drug resistance in the clinics

A Ulldemolins, J Seras-Franzoso, F Andrade… - Cancer Drug …, 2021 - ncbi.nlm.nih.gov
Advanced cancer is still considered an incurable disease because of its metastatic spread to
distal organs and progressive gain of chemoresistance. Even though considerable treatment …

Nanoparticle delivery of cancer drugs

AZ Wang, R Langer, OC Farokhzad - Annual review of medicine, 2012 - annualreviews.org
Nanomedicine, the application of nanotechnology to medicine, enabled the development of
nanoparticle therapeutic carriers. These drug carriers are passively targeted to tumors …

Role of integrated cancer nanomedicine in overcoming drug resistance

AK Iyer, A Singh, S Ganta, MM Amiji - Advanced drug delivery reviews, 2013 - Elsevier
Cancer remains a major killer of mankind. Failure of conventional chemotherapy has
resulted in recurrence and development of virulent multi drug resistant (MDR) phenotypes …

Nanoparticles as carriers for drug delivery in cancer

A Dadwal, A Baldi, R Kumar Narang - Artificial cells, nanomedicine …, 2018 - Taylor & Francis
Cancer nanotherapeutics are swiftly progressing and are being applied to solve several
limitations of conventional drug delivery systems such as non-specific biodistribution and …

Exploiting nanotechnology to overcome tumor drug resistance: challenges and opportunities

AR Kirtane, SM Kalscheuer, J Panyam - Advanced drug delivery reviews, 2013 - Elsevier
Tumor cells develop resistance to chemotherapeutic drugs through multiple mechanisms.
Overexpression of efflux transporters is an important source of drug resistance. Efflux …

Specific targeting cancer cells with nanoparticles and drug delivery in cancer therapy

S Raj, S Khurana, R Choudhari, KK Kesari… - Seminars in cancer …, 2021 - Elsevier
Nanotechnology has been the latest approach for diagnosis and treatment for cancer, which
opens up a new alternative therapeutic drug delivery option to treat disease. Nanoparticles …