Comprehensive RNA-sequencing analysis in peripheral blood cells reveals differential expression signatures with biomarker potential for idiopathic membranous …

N Wan, D Li, Z Zhou, Y Shao, S Zheng… - DNA and Cell …, 2019 - liebertpub.com
To date, the clinical course of idiopathic membranous nephropathy (iMN) remains unclear
and lacks direct and effective diagnostic methods. To better understand the host gene …

Integrative profiling of untreated primary membranous nephropathy at the single cell transcriptome level

Q Gu, Y Wen, X Cheng, Y Qi, X Cao, X Gao… - Clinical Kidney …, 2024 - academic.oup.com
Background Primary membranous nephropathy (PMN) is an autoimmune kidney disease.
Despite the identification of certain autoantigens, etiology and pathophysiology of the PMN …

MO124 THE SINGLE-CELL TRANSCRIPTOMIC OF HUMAN IDIOPATHIC MEMBRANOUS NEPHROPATHY

Y Zhong, Q Zhou - Nephrology Dialysis Transplantation, 2021 - academic.oup.com
Abstract Background and Aims Idiopathic membranous nephropathy (IMN) is an organ-
specific autoimmune disease of the kidney glomerulus. Although substantial advances have …

[HTML][HTML] Single-cell RNA sequencing shows the immune cell landscape in the kidneys of patients with idiopathic membranous nephropathy

M Shi, Y Wang, H Zhang, Z Ling, X Chen… - Frontiers in …, 2023 - frontiersin.org
Idiopathic membranous nephropathy (IMN) is a leading pathological type of the adult
primary nephrotic syndrome. Some patients develop end-stage renal disease due to poor …

Molecular characterization of membranous nephropathy

R Sealfon, L Mariani, C Avila-Casado… - Journal of the …, 2022 - journals.lww.com
Background Molecular characterization of nephropathies may facilitate pathophysiologic
insight, development of targeted therapeutics, and transcriptome-based disease …

Molecular Characterization of Membranous Nephropathy: Quo Vadis?

FC Fervenza, RJ Glassock - Journal of the American Society of …, 2022 - journals.lww.com
Membranous nephropathy (MN) is a common cause of nephrotic syndrome in adults. The
lesion of MN is a “pattern of injury,” not a specific diagnosis, which is based on finding bright …

[HTML][HTML] Proteomic analysis of glomeruli, tubules and renal interstitium in idiopathic membranous nephropathy (IMN): A statistically observational study

C Lu, ZF Luo, D Tang, F Zheng, S Li, S Liu, J Qiu, F Liu… - Medicine, 2023 - journals.lww.com
Idiopathic membranous nephropathy (IMN) is a common type of primary glomerulonephritis,
which pathogenesis are highly involved protein and immune regulation. Therefore, we …

[HTML][HTML] Single-cell profiling reveals transcriptional signatures and cell-cell crosstalk in anti-PLA2R positive idiopathic membranous nephropathy patients

J Xu, C Shen, W Lin, T Meng, JD Ooi… - Frontiers in …, 2021 - frontiersin.org
Idiopathic membranous nephropathy (IMN) is an organ-specific autoimmune disease of the
kidney glomerulus. It may gradually progress to end-stage renal disease (ESRD) …

[HTML][HTML] Identification of biomarkers related to immune and inflammation in membranous nephropathy: comprehensive bioinformatic analysis and validation

P Zhang, Y Geng, J Tang, Z Cao, X Xiang… - Frontiers in …, 2023 - frontiersin.org
Background Membranous nephropathy (MN) is an autoimmune glomerular disease that is
predominantly mediated by immune complex deposition and complement activation. The …

Identification and validation of biomarkers in membranous nephropathy and pan-cancer analysis

Y Yang, G Zou, X Wei, Z Zhang, L Zhuo, Q Xu… - Frontiers in …, 2024 - frontiersin.org
Background Membranous nephropathy (MN) is an autoimmune disease and represents the
most prevalent type of renal pathology in adult patients afflicted with nephrotic syndrome …