Association of Vitamin D receptor gene polymorphisms and clinical/severe outcomes of COVID-19 patients

R Abdollahzadeh, MH Shushizadeh… - Infection, Genetics and …, 2021 - Elsevier
Introduction Growing evidence documented the critical impacts of vitamin D (VD) in the
prognosis of COVID-19 patients. The functions of VD are dependent on the vitamin D …

VDR gene polymorphisms are associated with the increased susceptibility to COVID‐19 among iranian population: A case‐control study

A Jafarpoor, SM Jazayeri… - International Journal …, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is an infectious disease caused by the
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), but the pathogenesis is …

Effects of vitamin D receptor gene polymorphisms on the prognosis of COVID‐19

T Apaydin, H Polat, C Dincer Yazan, C Ilgin… - Clinical …, 2022 - Wiley Online Library
Purpose Vitamin D deficiency has emerged as another potential risk factor for coronavirus
disease (COVID‐19) due to the immunomodulatory effects of 25 hydroxyvitamin D [25 (OH) …

[HTML][HTML] Genetic variations of the vitamin D metabolic pathway and COVID-19 susceptibility and severity: current understanding and existing evidence

N Charoenngam, A Jaroenlapnopparat, SK Mettler… - Biomedicines, 2023 - mdpi.com
The immunomodulatory and metabolic effects of vitamin D receptor (VDR) activation have
been considered beneficial in mitigating the susceptibility and severity of COVID-19 …

[HTML][HTML] Vitamin D-related polymorphisms and vitamin D levels as risk biomarkers of COVID-19 disease severity

AT Freitas, C Calhau, G Antunes, B Araújo… - Scientific reports, 2021 - nature.com
Vitamin D is a fundamental regulator of host defences by activating genes related to innate
and adaptive immunity. Previous research shows a correlation between the levels of vitamin …

[HTML][HTML] Associations between genetic variants in the vitamin D metabolism pathway and severity of COVID-19 among UAE residents

F Al-Anouti, M Mousa, SN Karras, WB Grant… - Nutrients, 2021 - mdpi.com
Vitamin D has many effects on cells in the immune system. Many studies have linked low
vitamin D status with severity of COVID-19. Genetic variants involved in vitamin D …

[HTML][HTML] Using genetic variants to evaluate the causal effect of serum vitamin D concentration on COVID-19 susceptibility, severity and hospitalization traits: a …

Z Cui, Y Tian - Journal of Translational Medicine, 2021 - Springer
Background The coronavirus disease 2019 (COVID-19) pandemic has struck globally and is
exerting a devastating toll on humans. The pandemic has led to calls for widespread vitamin …

Genetic correlation, causal relationship, and shared loci between vitamin D and COVID‐19: A genome‐wide cross‐trait analysis

S Qiu, K Zheng, Y Hu, G Liu - Journal of Medical Virology, 2023 - Wiley Online Library
Observational studies have shown that vitamin D supplementation reduces the risk of
COVID‐19 infection, yet little is known about the shared genomic architectures between …

The role of DBP gene polymorphisms in the prevalence of new coronavirus disease 2019 infection and mortality rate

L Karcioglu Batur, N Hekim - Journal of Medical Virology, 2021 - Wiley Online Library
Abstract Since December 2019, coronavirus disease 2019 (COVID‐19), caused by severe
acute respiratory syndrome coronavirus 2, has given rise to emerging respiratory infections …

[HTML][HTML] Vitamin D deficiency and vitamin D receptor FokI polymorphism as risk factors for COVID-19

NMS Zeidan, HMAE Lateef, DM Selim, SA Razek… - Pediatric …, 2023 - nature.com
Background Given the sparse data on vitamin D status in pediatric COVID-19, we
investigated whether vitamin D deficiency could be a risk factor for susceptibility to COVID …