Ginsenosides as Anticancer Agents: In vitro and in vivo Activities, Structure–Activity Relationships, and Molecular Mechanisms of Action

SA Nag, JJ Qin, W Wang, MH Wang, H Wang… - Frontiers in …, 2012 - frontiersin.org
Conventional chemotherapeutic agents are often toxic not only to tumor cells but also to
normal cells, limiting their therapeutic use in the clinic. Novel natural product anticancer …

Anticancer activities of ginsenosides, the main active components of ginseng

H Hong, D Baatar, SG Hwang - … ‐Based Complementary and …, 2021 - Wiley Online Library
Cancer incidence rate has been increasing drastically in recent years. One of the many
cancer treatment methods is chemotherapy. Traditional medicine, in the form of …

Recent advances in ginseng as cancer therapeutics: a functional and mechanistic overview

AST Wong, CM Che, KW Leung - Natural product reports, 2015 - pubs.rsc.org
Covering: 2000 to 2014 Cancer is one of the leading causes of death worldwide. Ginseng, a
key ingredient in traditional Chinese medicine, shows great promise as a new treatment …

[HTML][HTML] Ginsenosides in cancer: A focus on the regulation of cell metabolism

W Yao, Y Guan - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Metabolic alterations play a key role in promoting tumor initiation and progression, leading
to extensive tumor heterogeneity and adaptability. Thus, targeting abnormal metabolic …

American ginseng: potential structure–function relationship in cancer chemoprevention

LW Qi, CZ Wang, CS Yuan - Biochemical pharmacology, 2010 - Elsevier
Ginseng has a prominent position on the list of best-selling herbal products in the world, and
its main active constituents are thought to be ginsenosides. Compared with the long history …

Functional mechanism of ginsenoside compound K on tumor growth and metastasis

J Liu, Y Wang, Z Yu, G Lv, X Huang… - Integrative cancer …, 2022 - journals.sagepub.com
Ginsenosides, as the most important constituents of ginseng, have been extensively
investigated in cancer chemoprevention and therapeutics. Among the ginsenosides …

In vitro anti-cancer activity and structure–activity relationships of natural products isolated from fruits of Panax ginseng

W Wang, Y Zhao, ER Rayburn, DL Hill, H Wang… - Cancer chemotherapy …, 2007 - Springer
Purpose Panax ginseng and its extracts have long been used for medical purposes; there is
increasing interest in developing ginseng products as cancer preventive or therapeutic …

Anticancer activities of protopanaxadiol‐and protopanaxatriol‐type ginsenosides and their metabolites

XJ Chen, XJ Zhang, YM Shui, JB Wan… - Evidence‐based …, 2016 - Wiley Online Library
Recently, most anticancer drugs are derived from natural resources such as marine,
microbial, and botanical sources, but the low success rates of chemotherapies and the …

Red ginseng and cancer treatment

W Chong-Zhi, S Anderson, DU Wei… - Chinese Journal of …, 2016 - Elsevier
The ginseng family, including Panax ginseng (Asian ginseng), Panax quinquefolius
(American ginseng), and Panax notoginseng (notoginseng), is commonly used herbal …

Anticancer effects of ginsenoside Rg3

M Sun, Y Ye, L Xiao, X Duan… - International …, 2017 - spandidos-publications.com
Cancer is a life-threatening disease with an alarmingly increased annual mortality rate
globally. Although various therapies are employed for cancer, the final effect is not …