For cancer screening to be successful, it should primarily detect cancers with lethal potential
or their precursors early, leading to therapy that reduces mortality and morbidity. Screening …

Over the past 30years, awareness and screening have led to an emphasis on early
diagnosis of cancer. Although the goals of these efforts were to reduce the rate oflate …

Background Cancer screening has the potential to prevent or reduce incidence and mortality
of the target disease, but may also be harmful and have unwanted side-effects. Methods …

Objective To determine the optimal method for quantifying and monitoring overdiagnosis in
cancer screening over time. Design Systematic review of primary research studies of any …

This article summarizes the phenomenon of cancer overdiagnosis—the diagnosis of a
“cancer” that would otherwise not go on to cause symptoms or death. We describe the two …

Several important lessons have been learnt from our experiences in screening for various
cancers. Screening programmes for cervical and colorectal cancers have had the greatest …

A vast range of disorders—from indolent to fast-growing lesions—are labelled as cancer.
Therefore, we believe that several changes should be made to the approach to cancer …

Screening in both healthy and high-risk populations offers the opportunity to detect cancer
early and with an increased opportunity for treatment and curative intent. Currently, a …

The aim of cancer screening is to detect asymptomatic cancers whose treatment will result in
extension of life, relative to length of life absent screening. Unfortunately, cancer screening …

From the mid‐20th century, accumulating evidence has supported the introduction of
screening for cancers of the cervix, breast, colon and rectum, prostate (via shared …