Epidemiological studies have clearly demonstrated a strong association between low birth
weight and long‐term renal disease. A potential mediator of this long‐term risk is a reduction …

In humans born at term, maximal nephron number is reached by the time nephrogenesis is
completed—at approximately 36 weeks' gestation. The number of nephrons does not …

Impaired kidney growth in low-birth-weight children: Distinct effects of maturity and weight for
gestational age. Background Low birth weight is an important risk factor for hypertension …

Low birth weight due to premature birth or to intrauterine growth retardation adversely affects
normal renal development. In the period immediately after birth, the short-term renal-related …

BACKGROUND: Premature birth and intrauterine growth restriction may increase the risk of
developing renal disease at adult age. Renal function may already be impaired at young …

Vascular placental insufficiency is considered a common pathogenic factor in human
intrauterine growth retardation (IUGR), resulting in small-for-gestational-age, asymmetric …

A low nephron number has been advocated to explain the association between intrauterine
growth restriction (IUGR) and hypertension in later life. IUGR not only leads to a low birth …

Long-term consequences of low birth weight. There is accumulating evidence of the impact
of low birth weight in adult age. Thus, the Barker theory and Brenner hypothesis gain more …

Low birth weight, nephron number, and kidney disease. More and more evidence is
emerging that highlights the far-reaching consequences of prenatal (intrauterine) …

Although the majority of preterm neonates now survive infancy, there is emerging
epidemiological evidence to demonstrate that individuals born preterm exhibit an elevated …