Background The role of adjuvant chemotherapy for patients with rectal cancer is
controversial, especially when used after preoperative chemoradiotherapy. Fluoropyrimidine …

PURPOSE We evaluated the role of oxaliplatin as adjuvant chemotherapy in patients with
rectal cancer who received preoperative chemoradiotherapy (CRT) with fluoropyrimidine …

Background EORTC trial 22921 examined the addition of preoperative or postoperative
chemotherapy to preoperative radiotherapy in patients with rectal cancer. After a median …

Background Preoperative chemoradiotherapy, total mesorectal excision surgery, and
adjuvant chemotherapy with fluorouracil is the standard combined modality treatment for …

Background Preoperative chemoradiotherapy with infusional fluorouracil, total mesorectal
excision surgery, and postoperative chemotherapy with fluorouracil was established by the …

For patients with high-risk stage II or stage III colon cancer, adjuvant chemotherapy with
fluoropyrimidine monotherapy reduces the risk of recurrence and death by approximately 20 …

Background The results of the recently published large European randomised study in rectal
cancer (European Organisation for Research and Treatment of Cancer 22921 trial) do not …

Purpose Adjuvant chemoradiotherapy after or before resection of high-risk rectal cancer
improves overall survival (OS) and pelvic control. We studied three postoperative …

The results of the PROCTOR-SCRIPT trial could not demonstrate a significant benefit of
adjuvant chemotherapy with fluoropyrimidine monotherapy regarding overall survival …

Background Treatment of locally advanced rectal cancer with chemoradiotherapy, surgery,
and adjuvant chemotherapy controls local disease, but distant metastases remain common …