Role of human brown fat in obesity, metabolism and cardiovascular disease: strategies to turn up the heat

JR Ruiz, B Martinez-Tellez, G Sanchez-Delgado… - Progress in …, 2018 - Elsevier
Human brown adipose tissue (BAT) was re-discovered in 2009 by several independent
groups, who showed that it is present and active in adults, as judged from the profound …

[HTML][HTML] Brown adipose tissue prevalence is lower in obesity but its metabolic activity is intact

OC Kulterer, CT Herz, M Prager… - Frontiers in …, 2022 - frontiersin.org
Due to its high metabolic activity, brown adipose tissue (BAT) has become a promising
target for the development of novel treatment concepts for metabolic disease. Despite …

MECHANISMS IN ENDOCRINOLOGY: Human brown adipose tissue as a therapeutic target: warming up or cooling down?

BT McNeill, KJ Suchacki… - European Journal of …, 2021 - academic.oup.com
Excessive accumulation of white adipose tissue leads to obesity and its associated
metabolic health consequences such as type 2 diabetes and cardiovascular disease …

Brown adipose tissue: The heat is on the heart

R Thoonen, AG Hindle… - American Journal of …, 2016 - journals.physiology.org
The study of brown adipose tissue (BAT) has gained significant scientific interest since the
discovery of functional BAT in adult humans. The thermogenic properties of BAT are well …

Biology and pathological implications of brown adipose tissue: promises and caveats for the control of obesity and its associated complications

P Tapia, M Fernández‐Galilea, F Robledo… - Biological …, 2018 - Wiley Online Library
The discovery of metabolically active brown adipose tissue (BAT) in adult humans has
fuelled the research of diverse aspects of this previously neglected tissue. BAT is solely …

Brown adipose tissue: an update on recent findings

KL Marlatt, E Ravussin - Current obesity reports, 2017 - Springer
Abstract Purpose of Review New treatment approaches to weight loss and weight loss
maintenance in humans are critical. Given its potential role in stimulating energy …

Impact of brown adipose tissue on body fatness and glucose metabolism in healthy humans

M Matsushita, T Yoneshiro, S Aita, T Kameya… - International journal of …, 2014 - nature.com
Background: Brown adipose tissue (BAT) is involved in the regulation of whole-body energy
expenditure and adiposity. Some clinical studies have reported an association between BAT …

Brown adipose tissue as a therapeutic target for human obesity

M Saito - Obesity research & clinical practice, 2013 - Elsevier
Brown adipose tissue (BAT) is the major site of sympathetically activated adaptive
thermogenesis during cold exposure and after spontaneous hyperphagia, thereby …

Brown adipose tissue: a potential target in the fight against obesity and the metabolic syndrome

L Poekes, N Lanthier, IA Leclercq - Clinical science, 2015 - portlandpress.com
BAT (brown adipose tissue) is the main site of thermogenesis in mammals. It is essential to
ensure thermoregulation in newborns. It is also found in (some) adult humans. Its capacity to …

Active brown adipose tissue is associated with a healthier metabolic phenotype in obesity

CT Herz, OC Kulterer, M Prager, C Schmöltzer… - Diabetes, 2022 - Am Diabetes Assoc
Obesity is associated with increasing cardiometabolic morbidity and mortality rates
worldwide. Not everyone with obesity, however, develops metabolic complications. Brown …