Molecular Frontiers in Melanoma: Pathogenesis, Diagnosis, and Therapeutic Advances

HJ Kim, YH Kim - International Journal of Molecular Sciences, 2024 - mdpi.com
Melanoma, a highly aggressive skin cancer, is characterized by rapid progression and high
mortality. Recent advances in molecular pathogenesis have shed light on genetic and …

Malignant melanoma in the 21st century: the emerging molecular landscape

A Sekulic, P Haluska Jr, AJ Miller, JG De Lamo… - Mayo Clinic …, 2008 - Elsevier
Malignant melanoma presents a substantial clinical challenge. Current diagnostic methods
are limited in their ability to diagnose early disease and accurately predict individual risk of …

Advances in melanoma: Epidemiology, diagnosis, and prognosis

S Waseh, JB Lee - Frontiers in Medicine, 2023 - frontiersin.org
Unraveling the multidimensional complexities of melanoma has required concerted efforts
by dedicated community of researchers and clinicians battling against this deadly form of …

Personalized medicine in malignant melanoma: towards patient tailored treatment

H Helgadottir, I Rocha Trocoli Drakensjö… - Frontiers in …, 2018 - frontiersin.org
Despite enormous international efforts, skin melanoma is still a major clinical challenge.
Melanoma takes a top place among the most common cancer types and it has one of the …

Towards therapeutic advances in melanoma management: An overview

S Singh, A Zafar, S Khan, I Naseem - Life Sciences, 2017 - Elsevier
Melanoma is one of the most aggressive types of skin cancer with rapidly increasing
incidence rate. The disease is largely considered incurable and the patients diagnosed with …

Novel biomarkers and therapeutic targets for melanoma

N Sabag, A Yakobson, M Retchkiman… - International Journal of …, 2022 - mdpi.com
Malignant melanoma is one of the most common cancers in the world. In the disease's early
stages, treatment involves surgery, in advanced stages however, treatment options were …

Toward a molecular classification of melanoma

LA Fecher, SD Cummings, MJ Keefe… - Journal of Clinical …, 2007 - ascopubs.org
The incidence of melanoma is increasing at one of the highest rates of any form of cancer in
the United States, with the current lifetime risk being one in 68. At present, there are limited …

Future perspectives in melanoma research. Meeting report from the" Melanoma Research: a bridge Naples-USA. Naples, December 6 th-7 th 2010"

PA Ascierto, E De Maio, S Bertuzzi, G Palmieri… - Journal of Translational …, 2011 - Springer
Progress in understanding the molecular basis of melanoma has made possible the
identification of molecular targets with important implications in clinical practice. In fact, new …

Melanoma: from melanocyte to genetic alterations and clinical options

C Bertolotto - Scientifica, 2013 - Wiley Online Library
Metastatic melanoma remained for decades without any effective treatment and was thus
considered as a paradigm of cancer resistance. Recent progress with understanding of the …

[HTML][HTML] Melanoma: molecular pathogenesis and therapeutic management

Y Liu, MS Sheikh - Molecular and cellular pharmacology, 2014 - ncbi.nlm.nih.gov
Malignant melanoma remains one of the fastest growing cancers worldwide. Although the
primary cutaneous melanoma can be managed by surgery, the advanced metastatic …