An advanced cone-and-plate reactor for the in vitro-application of shear stress on adherent cells

L Dreyer, B Krolitzki, R Autschbach… - Clinical …, 2011 - content.iospress.com
Endothelial cells (ECs) are permanently exposed to the blood flow and the resulting shear
stress, its magnitude varying with the EC site in the blood stream. Along with other …

[HTML][HTML] In vitro fluidic systems: Applying shear stress on endothelial cells

F Meng, H Cheng, J Qian, X Dai, Y Huang… - Medicine in Novel …, 2022 - Elsevier
Endothelial cells (ECs) that reside on the surface of blood vessels are constantly exposed to
mechanical stimulation, including shear stress. Fluid shear stress (FSS) controls multiple …

Endothelial cell response to biomechanical forces under simulated vascular loading conditions

MA Punchard, C Stenson-Cox, ED O'cearbhaill… - Journal of …, 2007 - Elsevier
In vivo, endothelial cells (EC) are constantly exposed to the haemodynamic forces (HF) of
pressure, wall shear stress and hoop stress. The main aim of this study was to design, create …

Design of a cone-and-plate device for controlled realistic shear stress stimulation on endothelial cell monolayers

M Franzoni, I Cattaneo, B Ene-Iordache, A Oldani… - Cytotechnology, 2016 - Springer
Endothelial cells are constantly exposed to blood flow and the resulting frictional force, the
wall shear stress, varies in magnitude and direction with time, depending on vasculature …

Engineering solutions for biological studies of flow-exposed endothelial cells on orbital shakers

A Fernandes, V Hosseini, V Vogel, RD Lovchik - PLoS One, 2022 - journals.plos.org
Shear stress is extremely important for endothelial cell (EC) function. The popularity of 6-well
plates on orbital shakers to impose shear stress on ECs has increased among biologists …

Vascular mechanobiology endothelial cell responses to fluid shear stress

J Ando, K Yamamoto - Circulation Journal, 2009 - jstage.jst.go.jp
Endothelial cells (ECs) lining blood vessel walls respond to shear stress, a fluid mechanical
force generated by flowing blood, and the EC responses play an important role in the …

[PDF][PDF] A simple parallel plate flow chamber to study effects of shear stress on endothelial cells

H Kaur, R Carriveau, B Mutus - Am. J. Biomed. Sci, 2012 - nwpii.com
In the present study, we report the construction of a parallel plate flow chamber for studying
the effects of shear stress in endothelial cells. This flow chamber is inexpensive and simple …

Quantitative measurement of shear-stress effects on endothelial cells

M Papadaki, LV Mclntire - Tissue Engineering Methods and Protocols, 1999 - Springer
Over the past 20 yr, great strides have been made toward understanding the role of fluid
hemodynamic forces in the vascular wall homeostasis at the molecular level. In vivo studies …

Segmenting growth of endothelial cells in 6-well plates on an orbital shaker for mechanobiological studies

KT Pang, M Ghim, M Arshad, X Wang… - JoVE (Journal of …, 2021 - jove.com
Shear stress imposed on the arterial wall by the flow of blood affects endothelial cell
morphology and function. Low magnitude, oscillatory and multidirectional shear stresses …

Modification of the swirling well cell culture model to alter shear stress metrics

M Arshad, S Cheng, M van Reeuwijk… - Biotechnology and …, 2023 - Wiley Online Library
Abstract Effects of hemodynamic shear stress on endothelial cells have been extensively
investigated using the “swirling well” method, in which cells are cultured in dishes or …