[HTML][HTML] Cancer-associated adipocytes: key players in breast cancer progression

Q Wu, B Li, Z Li, J Li, S Sun, S Sun - Journal of hematology & oncology, 2019 - Springer
Adipocytes are one of the primary stromal cells in many tissues, and they are considered to
play an active role in the tumor microenvironment. Cancer-associated adipocytes (CAAs) …

[HTML][HTML] Cancer-associated adipocytes in breast cancer: Causes and consequences

I Rybinska, N Mangano, E Tagliabue… - International journal of …, 2021 - mdpi.com
Breast cancer progression is highly dependent on the heterotypic interaction between tumor
cells and stromal cells of the tumor microenvironment. Cancer-associated adipocytes …

[HTML][HTML] Cancer-associated adipocytes: emerging supporters in breast cancer

C Zhao, M Wu, N Zeng, M Xiong, W Hu, W Lv… - Journal of Experimental …, 2020 - Springer
Breast cancer (BC) is a malignant breast tumor confronted with high invasion, metastasis
and recurrence rate, and adipocytes are the largest components in breast tissue. The …

[HTML][HTML] Multi‑faceted role of cancer‑associated adipocytes in the tumor microenvironment

H Yao, S He - Molecular Medicine Reports, 2021 - spandidos-publications.com
Adipocytes are a type of stromal cell found in numerous different tissues that serve an active
role in the tumor microenvironment. Cancer‑associated adipocytes (CAAs) display a …

[HTML][HTML] The fat and the bad: Mature adipocytes, key actors in tumor progression and resistance

MN Duong, A Geneste, F Fallone, X Li, C Dumontet… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Growing evidence has raised the important roles of adipocytes as an active player in the
tumor microenvironment. In many tumors adipocytes are in close contact with cancer cells …

Adipocyte biology in breast cancer: From silent bystander to active facilitator

J Choi, YJ Cha, JS Koo - Progress in lipid research, 2018 - Elsevier
Adipocytes account for the largest proportion among the cells that comprise breast tissue;
therefore, they are considered to be a critical cell type in the tumor microenvironment of …

[PDF][PDF] Adipocyte is a non-trivial, dynamic partner of breast cancer cells

J Tan, E Buache, MP Chenard… - International Journal …, 2011 - researchgate.net
While the participation of adipocytes is well known in tissue architecture, energy supply and
endocrine processes, their implication during natural cancer history is just beginning to …

Unraveling the obesity and breast cancer links: a role for cancer-associated adipocytes?

L Bochet, G Escourrou, P Valet, C Muller - Adipose Tissue …, 2010 - karger.com
In addition to diabetes and cardiovascular diseases, epidemiological evidence
demonstrates that people who are obese or overweight are at increased risk of developing …

Cancer-associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion

B Dirat, L Bochet, M Dabek, D Daviaud, S Dauvillier… - Cancer research, 2011 - AACR
Early local tumor invasion in breast cancer results in a likely encounter between cancer cells
and mature adipocytes, but the role of these fat cells in tumor progression remains unclear …

Adipocytes: impact on tumor growth and potential sites for therapeutic intervention

S Hefetz-Sela, PE Scherer - Pharmacology & therapeutics, 2013 - Elsevier
The prevalence of obesity has increased dramatically in recent decades, reaching epidemic
proportions. It is becoming clear that obesity is associated not only with type 2 diabetes …