Gut-derived bacterial LPS attenuates incubation of methamphetamine craving via modulating microglia

Z Yu, W Chen, L Zhang, Y Chen, W Chen… - Brain, behavior, and …, 2023 - Elsevier
Background The microbiota-gut-brain axis plays a critical role in the pathophysiology of
neuropsychiatric disorders, and the compositions of gut microbiota are altered by addictive …

Alterations in gut microbiota affect behavioral and inflammatory responses to methamphetamine in mice

S Lai, J Wang, B Wang, R Wang, G Li, Y Jia, T Chen… - …, 2022 - Springer
Rationale and objectives Methamphetamine (METH) is a highly addictive and widely
abused drug that causes severe neuroinflammation in the human brain. The gut microbiota …

Methamphetamine exposure and its cessation alter gut microbiota and induce depressive-like behavioral effects on rats

S Forouzan, KL Hoffman, TA Kosten - Psychopharmacology, 2021 - Springer
Rationale Methamphetamine is a highly abused psychostimulant drug and its use remains a
major public health concern worldwide with limited effective treatment options. Accumulative …

Exploring the role and mechanism of gut microbiota in methamphetamine addiction using antibiotic treatment followed by fecal microbiota transplantation

Q Wang, X Guo, Q Yue, S Zhu, L Guo, G Li… - The Anatomical …, 2023 - Wiley Online Library
Recently, the role of the gut microbiota in the context of drug addiction has attracted the
attention of researchers; however, the specific effects and underlying mechanisms require …

[HTML][HTML] Altered fecal microbiota correlated with systemic inflammation in male subjects with methamphetamine use disorder

D Deng, H Su, Y Song, T Chen, Q Sun… - Frontiers in cellular …, 2021 - frontiersin.org
Methamphetamine use disorder (MUD) is a major public health problem worldwide with
limited effective treatment options. Previous studies have reported methamphetamine …

Differential perturbations of gut microbial profiles and co‐occurrence networks among phases of methamphetamine‐induced conditioned place preference

Y Wang, J Zhang, C Deji, J Fan, X Miao… - Journal of …, 2021 - Wiley Online Library
The gut–brain axis provides a pathway for the interaction between gut microbiota and
methamphetamine (METH) addiction. However, the gut microbial signatures during different …

[HTML][HTML] Gut microbiota analysis in rats with methamphetamine-induced conditioned place preference

T Ning, X Gong, L Xie, B Ma - Frontiers in microbiology, 2017 - frontiersin.org
Methamphetamine abuse is a major public health crisis. Because accumulating evidence
supports the hypothesis that the gut microbiota plays an important role in central nervous …

[HTML][HTML] Methamphetamine disturbs gut homeostasis and reshapes serum metabolome, inducing neurotoxicity and abnormal behaviors in mice

KK Zhang, LJ Chen, JH Li, JL Liu, LB Wang… - Frontiers in …, 2022 - frontiersin.org
As an illicit psychostimulant, repeated methamphetamine (MA) exposure results in addiction
and causes severe neurotoxicity. Studies have revealed complex interactions among gut …

[HTML][HTML] The microbiome–gut–brain axis, a potential therapeutic target for substance-related disorders

X Fu, T Chen, J Cai, B Liu, Y Zeng… - Frontiers in microbiology, 2021 - frontiersin.org
Substance addiction is a complex worldwide public health problem. It endangers both
personal life and social stability, causing great loss on economy. Substance-related disorder …

Methamphetamine induces intestinal injury by altering gut microbiota and promoting inflammation in mice

LB Wang, LL Xu, LJ Chen, KK Zhang, QY Zhang… - Toxicology and Applied …, 2022 - Elsevier
Methamphetamine (METH) is a psychostimulant abused worldwide. Its abuse induces
intestinal toxicity. Moreover, the gut microbiota is altered by drugs, which induces intestinal …