Management strategies and future directions for systemic lupus erythematosus in adults

L Durcan, T O'Dwyer, M Petri - The Lancet, 2019 - thelancet.com
Systemic lupus erythematosus (SLE) is an autoimmune disease characterised by the loss of
self-tolerance and formation of nuclear autoantigens and immune complexes resulting in …

Novel paradigms in systemic lupus erythematosus

T Dörner, R Furie - The Lancet, 2019 - thelancet.com
The heterogeneity of systemic lupus erythematosus (SLE), long recognised by clinicians, is
now challenging the entire lupus community, from geneticists to clinical investigators …

The Asia-Pacific League of Associations for Rheumatology consensus statements on the management of systemic lupus erythematosus

CC Mok, L Hamijoyo, N Kasitanon, S Chen… - The Lancet …, 2021 - thelancet.com
Systemic lupus erythematosus (SLE) is prevalent in Asia and carries a variable prognosis
among patients across the Asia-Pacific region, which could relate to access to health care …

Update οn the diagnosis and management of systemic lupus erythematosus

A Fanouriakis, N Tziolos, G Bertsias… - Annals of the rheumatic …, 2021 - ard.bmj.com
Clinical heterogeneity, unpredictable course and flares are characteristics of systemic lupus
erythematosus (SLE). Although SLE is—by and large—a systemic disease, occasionally it …

New therapeutic strategies in systemic lupus erythematosus management

M Gatto, M Zen, L Iaccarino, A Doria - Nature Reviews Rheumatology, 2019 - nature.com
The current treatment approach for systemic lupus erythematosus (SLE), as outlined in the
recommendations by international medical associations including EULAR and the ACR, is …

The main challenges in systemic lupus erythematosus: where do we stand?

M Piga, L Arnaud - Journal of clinical medicine, 2021 - mdpi.com
Systemic lupus erythematosus (SLE) is an immune-mediated multi-systemic disease
characterized by a wide variability of clinical manifestations and a course frequently subject …

Unmet medical needs in systemic lupus erythematosus

A Lateef, M Petri - Arthritis research & therapy, 2012 - Springer
Systemic lupus erythematosus (SLE) is an autoimmune disease of diverse manifestations,
with onset usually in young women in the third to fourth decade of life. The chronic nature of …

Systemic lupus erythematosus: state of the art on clinical practice guidelines

F Tamirou, L Arnaud, R Talarico, CA Scirè… - RMD open, 2019 - rmdopen.bmj.com
Systemic lupus erythematosus (SLE) is the paradigm of systemic autoimmune diseases
characterised by a wide spectrum of clinical manifestations with an unpredictable relapsing …

Systemic lupus erythematosus: one year in review 2023

D Zucchi, E Silvagni, E Elefante, V Signorini… - Clinical and …, 2023 - sfera.unife.it
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a wide range of
clinical manifestations and a relapsing-remitting course. New data regarding pathogenic …

Systemic lupus erythematosus (SLE) therapy: the old and the new

F Basta, F Fasola, K Triantafyllias… - Rheumatology and …, 2020 - Springer
Despite recent improvements in the treatment of systemic lupus erythematosus (SLE),
disease activity, comorbidities and drug toxicity significantly contribute to the risk of …