Background There is renewed acknowledgement that targeting gametocytes is essential for
malaria control and elimination efforts. Simple mathematical models were fitted to data from …

Background The aim of this study was to identify and compare factors associated with
Plasmodium falciparum gametocyte carriage in three regions of differing malaria endemicity …

Background Plasmodium falciparum gametocytes, specifically mature stages, are the only
stage in man transmissible to the mosquito vector responsible for malaria transmission. Anti …

Background Gametocytes are responsible for transmission of malaria from human to
mosquito. Artemisinin combination therapy (ACT) reduces post-treatment gametocyte …

It is the mature gametocytes of Plasmodium that are solely responsible for parasite
transmission from the mammalian host to the mosquito. They are therefore a logical target …

Plasmodium falciparum malaria is one of mankind's main killers. Part of the parasite's life-
cycle is spent in human blood, mainly as asexual stages. A fraction of the asexual parasites …

Background: Malaria elimination strategies require a thorough understanding of parasite
transmission from human to mosquito. A clinical model to induce gametocytes to understand …

Gametocytes are the sexual stage of the malaria parasite and are essential for transmission
to the mosquito. Antimalarial drugs have been reported to affect gametocyte production in …

The transmission of malaria parasites depends on the presence of sexual stages
(gametocytes) in the blood, making the ratio and densities of female and male gametocytes …

Background Recent renewed emphasis on the eradication of malaria has highlighted the
need for more tools with which to achieve this ambitious goal. One high priority area is the …