Putative virulence factors of Aspergillus fumigatus

Tomee, Kauffman - Clinical & Experimental Allergy, 2000 - Wiley Online Library
Various putative virulence factors of Aspergillus fumigatus have been studied over the past
decades. A. fumigatus gliotoxin is a potent inhibitor of the mucociliary system. Several fungal …

[HTML][HTML] Expression and secretion of Aspergillus fumigatus proteases are regulated in response to different protein substrates

E Farnell, K Rousseau, DJ Thornton, P Bowyer… - Fungal biology, 2012 - Elsevier
The ubiquitous filamentous fungus Aspergillus fumigatus secretes a number of allergens
with protease activity and has been linked to a variety of allergic conditions such as Severe …

The search for virulence determinants in Aspergillus fumigatus

JP Bouchara, G Tronchin, G Larcher, D Chabasse - Trends in Microbiology, 1995 - cell.com
The development of aspergillosis in an immunodeficient host depends on interactions
between fungal and host components. The recognition by Aspergillus fumigatus of …

Aspergillus fumigatus allergen I, a major IgE-binding protein, is a member of the mitogillin family of cytotoxins.

LK Arruda, TA Platts-Mills, JW Fox… - The Journal of …, 1990 - rupress.org
A major 18-kD IgE-binding protein from Aspergillus fumigatus (Asp fI) has been purified.
Partial amino acid sequencing of Asp f I showed extensive sequence homology (95%) …

Aspergillus fumigatus: contours of an opportunistic human pathogen

A McCormick, J Loeffler, F Ebel - Cellular microbiology, 2010 - Wiley Online Library
Aspergillus fumigatus is currently the major air‐borne fungal pathogen. It is able to cause
several forms of disease in humans of which invasive aspergillosis is the most severe. The …

Selective expression of a major allergen and cytotoxin, Asp f I, in Aspergillus fumigatus. Implications for the immunopathogenesis of Aspergillus-related diseases.

LK Arruda, BJ Mann, MD Chapman - Journal of immunology …, 1992 - journals.aai.org
Asp f I is a major 18-kDa Aspergillus fumigatus allergen and a member of the mitogillin
family of cytotoxins. The nucleotide sequence of the Asp f I gene was determined by …

The pathobiology of Aspergillus fumigatus

JP Latgé - Trends in microbiology, 2001 - cell.com
Aspergillus fumigatus is the most prevalent airborne fungal pathogen in developed
countries, and in immunocompromised patients causes a usually fatal invasive aspergillosis …

Aspergillus fumigatus: Principles of Pathogenesis and Host Defense

TM Hohl, M Feldmesser - Eukaryotic cell, 2007 - Am Soc Microbiol
Aspergillus fumigatus is a ubiquitous saprophytic mold (67) that forms airborne spores
(conidia). Humans inhale, on average, hundreds of these infectious propagules daily. In …

[HTML][HTML] Aspergillus fumigatus—What Makes the Species a Ubiquitous Human Fungal Pathogen?

KJ Kwon-Chung, JA Sugui - PLoS pathogens, 2013 - journals.plos.org
Aspergillus fumigatus, the major cause of life threatening invasive aspergillosis (IA), is a
ubiquitous saprophytic fungus to which humans are exposed daily in most parts of the world …

Correlation between Gliotoxin Production and Virulence of Aspergillus fumigatus in Galleria mellonella

EP Reeves, CGM Messina, S Doyle, K Kavanagh - Mycopathologia, 2004 - Springer
Aspergillus fumigatus is a pathogenic fungus capable of causing both allergic lung disease
and invasive aspergillosis, a serious, life-threatening condition in neutropenic patients …