[HTML][HTML] Human embryonic stem cells derived by somatic cell nuclear transfer

M Tachibana, P Amato, M Sparman, NM Gutierrez… - Cell, 2013 - cell.com
Reprogramming somatic cells into pluripotent embryonic stem cells (ESCs) by somatic cell
nuclear transfer (SCNT) has been envisioned as an approach for generating patient …

Epigenetic modification is central to genome reprogramming in somatic cell nuclear transfer

L Armstrong, M Lako, W Dean, M Stojkovic - Stem cells, 2006 - academic.oup.com
The recent high-profile reports of the derivation of human embryonic stem cells (ESCs) from
human blastocysts produced by somatic cell nuclear transfer (SCNT) have highlighted the …

[HTML][HTML] Human somatic cell nuclear transfer using adult cells

YG Chung, JH Eum, JE Lee, SH Shim, V Sepilian… - Cell stem cell, 2014 - cell.com
Derivation of patient-specific human pluripotent stem cells via somatic cell nuclear transfer
(SCNT) has the potential for applications in a range of therapeutic contexts. However …

Equivalency of nuclear transfer‐derived embryonic stem cells to those derived from fertilized mouse blastocysts

S Wakayama, ML Jakt, M Suzuki, R Araki, T Hikichi… - Stem …, 2006 - academic.oup.com
Therapeutic cloning, whereby nuclear transfer (NT) is used to generate embryonic stem cells
(ESCs) from blastocysts, has been demonstrated successfully in mice and cattle. However, if …

[HTML][HTML] Embryogenesis and blastocyst development after somatic cell nuclear transfer in nonhuman primates: overcoming defects caused by meiotic spindle …

C Simerly, C Navara, SH Hyun, BC Lee, SK Kang… - Developmental …, 2004 - Elsevier
Therapeutic cloning or nuclear transfer for stem cells (NTSC) seeks to overcome immune
rejection through the development of embryonic stem cells (ES cells) derived from cloned …

Producing primate embryonic stem cells by somatic cell nuclear transfer

JA Byrne, DA Pedersen, LL Clepper, M Nelson… - Nature, 2007 - nature.com
Derivation of embryonic stem (ES) cells genetically identical to a patient by somatic cell
nuclear transfer (SCNT) holds the potential to cure or alleviate the symptoms of many …

Reprogramming mammalian somatic cells

N Rodriguez-Osorio, R Urrego, JB Cibelli, K Eilertsen… - Theriogenology, 2012 - Elsevier
Somatic cell nuclear transfer (SCNT), the technique commonly known as cloning, permits
transformation of a somatic cell into an undifferentiated zygote with the potential to develop …

Nuclear reprogramming of cloned embryos and its implications for therapeutic cloning

X Yang, SL Smith, XC Tian, HA Lewin, JP Renard… - Nature …, 2007 - nature.com
Therapeutic cloning, whereby somatic cell nuclear transfer (SCNT) is used to generate
patient-specific embryonic stem cells (ESCs) from blastocysts cloned by nuclear transfer …

[HTML][HTML] Somatic cell nuclear transfer reprogramming: mechanisms and applications

S Matoba, Y Zhang - Cell stem cell, 2018 - cell.com
Successful cloning of monkeys, the first non-human primate species, by somatic cell nuclear
transfer (SCNT) attracted worldwide attention earlier this year. Remarkably, it has taken …

A new, dynamic era for somatic cell nuclear transfer?

P Loi, D Iuso, M Czernik, A Ogura - Trends in biotechnology, 2016 - cell.com
Cloning animals by somatic cell nuclear transfer (SCNT) has remained an uncontrollable
process for many years. High rates of embryonic losses, stillbirths, and postnatal mortality …