In vivo imaging and regression analysis reveal cell-non-autonomous functions of Shroom3 during neural tube closure

AT Baldwin, JH Kim, JB Wallingford - bioRxiv, 2022 - biorxiv.org
During neural tube closure, neural ectoderm cells constrict their apical surfaces to bend and
fold the tissue into a tube that will become the central nervous system. These cells are …

Global analysis of cell behavior and protein localization dynamics reveals region-specific functions for Shroom3 and N-cadherin during neural tube closure

AT Baldwin, J Kim, JB Wallingford - bioRxiv, 2021 - biorxiv.org
Failures of neural tube closure are common and serious birth defects, yet we have a poor
understanding of the interaction of genetics and cell biology during neural tube closure …

[HTML][HTML] Correction: Global analysis of cell behavior and protein dynamics reveals region-specific roles for Shroom3 and N-cadherin during neural tube closure

AT Baldwin, J Kim, H Seo, JB Wallingford - eLife, 2024 - elifesciences.org
Correction: Global analysis of cell behavior and protein dynamics reveals region-specific
roles for Shroom3 and N-cadherin during neural tube closure | eLife Skip to Content eLife …

[HTML][HTML] In vivo high-content imaging and regression analysis reveal non-cell autonomous functions of Shroom3 during neural tube closure

AT Baldwin, JH Kim, JB Wallingford - Developmental biology, 2022 - Elsevier
During neural tube closure, neural ectoderm cells constrict their apical surfaces to bend and
fold the tissue into a tube that will become the central nervous system. Recent data from …

Global analysis of cell behavior and protein dynamics reveals region-specific roles for Shroom3 and N-cadherin during neural tube closure

AT Baldwin, JH Kim, H Seo, JB Wallingford - Elife, 2022 - elifesciences.org
Failures of neural tube closure are common and serious birth defects, yet we have a poor
understanding of the interaction of genetics and cell biology during neural tube closure …

Wnt4 and ephrinB2 instruct apical constriction via Dishevelled and non-canonical signaling

J Yoon, J Sun, M Lee, YS Hwang, IO Daar - Nature communications, 2023 - nature.com
Apical constriction is a cell shape change critical to vertebrate neural tube closure, and the
contractile force required for this process is generated by actin-myosin networks. The …

Prickle2 regulates apical junction remodeling and tissue fluidity during vertebrate neurulation

M Matsuda, SY Sokol - bioRxiv, 2024 - biorxiv.org
The process of folding the flat neuroectoderm into an elongated neural tube depends on
tissue fluidity, a property that allows epithelial deformation while preserving tissue integrity …

Shroom3 functions downstream of planar cell polarity to regulate myosin II distribution and cellular organization during neural tube closure

EM McGreevy, D Vijayraghavan, LA Davidson… - Biology …, 2015 - journals.biologists.com
Neural tube closure is a critical developmental event that relies on actomyosin contractility to
facilitate specific processes such as apical constriction, tissue bending, and directional cell …

Lulu regulates Shroom-induced apical constriction during neural tube closure

CW Chu, E Gerstenzang, O Ossipova, SY Sokol - PLoS One, 2013 - journals.plos.org
Apical constriction is an essential cell behavior during neural tube closure, but its underlying
mechanisms are not fully understood. Lulu, or EPB4. 1l5, is a FERM domain protein that has …

α-catenin phosphorylation is elevated during mitosis to resist apical rounding and epithelial barrier leak

PM Le, JM Quinn, AWT Steffeck, AS Flozak, CF Huang… - bioRxiv, 2024 - biorxiv.org
Epithelial cell cohesion and barrier function critically depend on α-catenin, an actin-binding
protein and essential constituent of cadherin-catenin-based adherens junctions. α-catenin …