Ribosome and protein synthesis lie at the core of cell growth and are major consumers of
the cellular budget. Here we review recent progress in the coupling of ribosome synthesis …

Cell growth relies upon the ability to produce new proteins, which requires energy and
chemical precursors, and an adequate supply of the molecular machines for protein …

A large number of ribosome synthesis factors have been identified using proteomic analyses
in yeast. The patterns of RNA and protein co-precipitation suggest that ribosome synthesis …

Ribosomes provide the basis for protein production and this drives cell growth. Recent
studies, both in yeast and in higher eukaryotes, are beginning to reveal new mechanisms …

Although the importance of cell growth for cell-cycle progression has been recognized for
thirty years, the molecular basis of this relationship is poorly understood. However …

For cells to grow faster they must increase their protein production rate. Microorganisms
have traditionally been thought to accomplish this increase by producing more ribosomes to …

Protein homeostasis of bacterial cells is maintained by coordinated processes of protein
production, folding, and degradation. Translational efficiency of a given mRNA depends on …

Ribosomes are large ribozymes that synthesize all cellular proteins. As protein synthesis is
rate‐limiting for bacterial growth and ribosomes can comprise a large portion of the cellular …

Translation is one of the final steps that regulate gene expression. The ribosome is the
effector of translation through to its role in mRNA decoding and protein synthesis. Many …

The stage at which ribosomes are recruited to messenger RNAs (mRNAs) is an elaborate
and highly regulated phase of protein synthesis. Upon completion of this step, a ribosome is …