18F-DOPA uptake does not correlate with IDH mutation status and 1p/19q co-deletion in glioma

F Cicone, L Carideo, C Scaringi, A Arcella… - Annals of nuclear …, 2019 - Springer
Objective The role of amino acid positron emission tomography (PET) in glioma grading and
outcome prognostication has not yet been well established. This is particularly true in the …

IDH mutation is paradoxically associated with higher 18F-FDOPA PET uptake in diffuse grade II and grade III gliomas

A Verger, P Metellus, Q Sala, C Colin, E Bialecki… - European journal of …, 2017 - Springer
Abstract Purpose The World Health Organization Classification of Tumors of the Central
Nervous System has recently been updated by the integration of diagnostic and prognostic …

[HTML][HTML] Multi-tracer and multiparametric PET imaging to detect the IDH mutation in glioma: a preclinical translational in vitro, in vivo, and ex vivo study

A Clément, T Zaragori, R Filosa, O Ovdiichuk… - Cancer Imaging, 2022 - Springer
Background This translational study explores multi-tracer PET imaging for the non-invasive
detection of the IDH1 mutation which is a positive prognostic factor in glioma. Methods U87 …

Maximum uptake and hypermetabolic volume of 18F-FDOPA PET estimate molecular status and overall survival in low-grade gliomas: a PET and MRI study

H Tatekawa, J Yao, TC Oughourlian… - Clinical nuclear …, 2020 - journals.lww.com
Purpose We evaluated 18 F-FDOPA PET and MRI characteristics in association with the
molecular status and overall survival (OS) in a large number of low-grade gliomas (LGGs) …

Static and dynamic 18F–FET PET for the characterization of gliomas defined by IDH and 1p/19q status

A Verger, G Stoffels, EK Bauer, P Lohmann… - European journal of …, 2018 - Springer
Purpose The molecular features isocitrate dehydrogenase (IDH) mutation and 1p/19q co-
deletion have gained major importance for both glioma typing and prognosis and have …

Prediction of overall survival based on isocitrate dehydrogenase 1 mutation and 18F-FDG uptake on PET/CT in patients with cerebral gliomas

D Kim, S Kim, SH Kim, JH Chang… - Clinical nuclear …, 2018 - journals.lww.com
Purpose This retrospective study aimed to correlate 18 F-FDG uptake on PET/CT with
isocitrate dehydrogenase enzyme isoform 1 (IDH1) mutation in patients with cerebral …

A high 18F-FDOPA uptake is associated with a slow growth rate in diffuse Grade II–III gliomas

S Isal, G Gauchotte, F Rech, M Blonski… - The British Journal of …, 2018 - academic.oup.com
Objective: In diffuse Grade II–III gliomas, a high3, 4-dihydroxy-6-(18F)-fluoro-L-
phenylalanine (18F-FDOPA) positron emission tomography (PET) uptake, with a …

Is the information provided by amino acid PET radiopharmaceuticals clinically equivalent in gliomas?

A Verger, D Taieb, E Guedj - European Journal of Nuclear Medicine and …, 2017 - Springer
Dear Sir, Over the past few years, brain tumor imaging has been evaluated with several
radiolabeled amino acid radiopharmaceuticals for which the increased uptake is classically …

[HTML][HTML] Dynamic amino-acid PET in neuro-oncology: a prognostic tool becomes essential

A Verger, L Imbert, T Zaragori - European Journal of Nuclear Medicine and …, 2021 - Springer
Amino-acid PET imaging is an efficient complementary tool to MRI for the assessment of
gliomas, principally for high-grade gliomas [1] and is now recommended by the Response …

Non-invasive prediction of IDH-wildtype genotype in gliomas using dynamic 18F-FET PET

F Vettermann, B Suchorska, M Unterrainer… - European journal of …, 2019 - Springer
Purpose According to the updated WHO classification of gliomas with its emphasis on
molecular parameters, tumours with an IDH-wildtype status have a dismal prognosis. To …