Actions of symbiotic gut microbiota are in dynamic balance with the host's organism to
maintain homeostasis. Many different factors have an impact on this relationship, including …

Background: Increasing evidence proves the pivotal role of gut microbiota in mammals'
homeostasis. Gut bacterial metabolites may exert local effects on the intestines, and may …

In a complex, diverse intestinal environment, commensal microbiota metabolizes excessive
dietary tryptophan to produce more bioactive metabolites connecting with kinds of diverse …

Tryptophan is an important dietary amino acid and it is the precursor for 5‐
hydroxytryptamine synthesis in the nervous system and by enterochromaffin cells in the gut …

Increasing evidence suggests that metabolites produced by the gut microbiota play a crucial
role in host–microbe interactions. Dietary tryptophan ingested by the host enters the gut …

Tryptophan is an essential amino acid from dietary proteins. It can be metabolized into
different metabolites in both the gut microbiota and tissue cells. Tryptophan metabolites such …

At present, a large number of relevant studies have suggested that the changes in gut
microbiota are related to the course of nervous system diseases, and the microbiota-gut …

The intestine has a major role in the digestion and absorption of nutrients, and gut barrier is
the first defense line against harmful pathogens. Alteration of the intestinal barrier is …

Inflammatory bowel diseases (IBD), which comprise Crohn's disease and ulcerative colitis,
are chronic intestinal disorders with an increased prevalence and incidence over the last …

The gut microbiota is a crucial actor in human physiology. Many of these effects are
mediated by metabolites that are either produced by the microbes or derived from the …