[HTML][HTML] Characterization of immune responses associated with ERAP-1 expression in HSV-induced Behçet's disease mouse model
Behçet's disease (BD) is a chronic multisystem inflammatory disorder. Endoplasmic
reticulum aminopeptidase 1 (ERAP1) polymorphism has been reported as a risk factor for …
reticulum aminopeptidase 1 (ERAP1) polymorphism has been reported as a risk factor for …
Genotyping of Italian patients with Behçet syndrome identified two novel ERAP1 polymorphisms using sequencing-based approach
MC Padula, P Leccese, N Lascaro, T Carbone… - Human Immunology, 2019 - Elsevier
The endoplasmic reticulum aminopeptidase protein 1 gene (ERAP1) is related to several
human diseases, including Behçet syndrome (BS), a multisystemic disorder with unknown …
human diseases, including Behçet syndrome (BS), a multisystemic disorder with unknown …
Distribution of rs17482078 and rs27044 ERAP1 polymorphisms in a group of Italian Behçet's syndrome patients: a preliminary case–control study
MC Padula, P Leccese, E Pellizzieri, AA Padula… - Internal and Emergency …, 2019 - Springer
The Endoplasmic reticulum aminopeptidase protein 1 (ERAP1) trims N-terminal amino acids
from epitope precursors for Major Histocompatibility Complex class I presentation. Genome …
from epitope precursors for Major Histocompatibility Complex class I presentation. Genome …
From structure to function for the characterization of ERAP1 active site in Behçet syndrome. A novel polymorphism associated with known gene variations
MC Padula, P Leccese, N Lascaro, T Carbone… - Molecular …, 2020 - Elsevier
Introduction ERAP1 has been recently proposed as risk marker of Behçet syndrome (BS).
Gene single nucleotide polymorphisms (SNPs) could affect the enzymatic activity and the …
Gene single nucleotide polymorphisms (SNPs) could affect the enzymatic activity and the …
[PDF][PDF] The correlation of endoplasmic reticulum aminopeptidase 1 polymorphisms with Behçet's disease: a meta-analysis
W Gao, X Jin, P Zhou, H Zhu, K Xie… - Clinical and …, 2023 - clinexprheumatol.org
Objective Substantial evidence has highlighted the mediation of endoplasmic reticulum
aminopeptidase 1 (ERAP1) in the onset of Behçet's disease (BD), which can be differentially …
aminopeptidase 1 (ERAP1) in the onset of Behçet's disease (BD), which can be differentially …
Variant in ERAP1 promoter region is associated with low expression in a patient with a Behçet-like MHC-I-opathy
C Dimopoulou, JD Lundgren, J Sundal… - Journal of Human …, 2020 - nature.com
Behçet disease (BD) is an immune-mediated disease. The cause of BD remains unknown,
but the existence of multiple pathological pathways is suspected, including different genetic …
but the existence of multiple pathological pathways is suspected, including different genetic …
[HTML][HTML] ERAP1 polymorphisms interactions and their association with Behçet's disease susceptibly: Application of Model-Based Multifactor Dimension Reduction …
Background Behçet's disease (BD) is a chronic multi-systemic vasculitis with a considerable
prevalence in Asian countries. There are many genes associated with a higher risk of …
prevalence in Asian countries. There are many genes associated with a higher risk of …
[HTML][HTML] Epistatic Interaction of ERAP1 and HLA-B*51 in Iranian Patients with Behçet's Disease
Behçet's Disease (BD) pathogenesis remains unclear, but some genetic loci and
environmental factors are proposed to play a role. Here, we investigate the association of …
environmental factors are proposed to play a role. Here, we investigate the association of …
Autoimmune disease-associated variants of extracellular endoplasmic reticulum aminopeptidase 1 induce altered innate immune responses by human immune cells
YA Aldhamen, Y Pepelyayeva, DPW Rastall… - Journal of innate …, 2015 - karger.com
Abstract Endoplasmic reticulum aminopeptidase 1 (ERAP1) gene polymorphisms have
been linked to several autoimmune diseases; however, the molecular mechanisms …
been linked to several autoimmune diseases; however, the molecular mechanisms …
The role of ERAP1 in autoinflammation and autoimmunity
Y Pepelyayeva, A Amalfitano - Human immunology, 2019 - Elsevier
Autoimmune and autoinflammatory diseases affect millions worldwide. These classes of
disease involve abnormal immune activation of both the innate and adaptive immune …
disease involve abnormal immune activation of both the innate and adaptive immune …