The cell cycle is a series of events by which cellular components are accurately segregated
into daughter cells, principally controlled by the oscillating activities of cyclin-dependent …

Post-translational modification of proteins with ubiquitin plays a central role in regulating
numerous cellular processes. E3 ligases determine the specificity of ubiquitination by …

Emerging clinical evidence shows that the deregulation of ubiquitin-mediated degradation of
oncogene products or tumour suppressors is likely to be involved in the aetiology of …

Ubiquitination is one of the posttranslational modifications that regulates a number of
intracellular events including signal transduction, protein quality control, transcription, cell …

The tripartite-motif (TRIM) family of proteins represents one of the largest classes of putative
single protein RING-finger E3 ubiquitin ligases. The members of this family are …

Cancer is the second leading cause of human death across the world. Tripartite motif (TRIM)
family, with E3 ubiquitin ligase activities in majority of its members, is reported to be involved …

Tripartite motif (TRIM) family proteins, most of which have E3 ubiquitin ligase activities, have
various functions in cellular processes including intracellular signaling, development …

TRIM proteins play important roles in a wide range of biological processes, including cell
proliferation, differentiation, development, apoptosis, oncogenesis and innate immunity [1 …

The TRIM family is composed of multidomain ubiquitin E3 ligases characterized by the
presence of the N‐terminal tripartite motif (RING, B‐boxes, and coiled coil). TRIM proteins …

The tripartite-motif (TRIM) family represents one of the largest classes of putative single
protein RING-finger E3 ubiquitin ligases. TRIM family is involved in a variety of cellular …