Improved supportive care, more precise risk stratification, and personalized chemotherapy
based on the characteristics of leukemic cells and hosts (eg, pharmacokinetics and …

Clinical trials have advanced the cure rate of childhood acute lymphoblastic leukaemia to
near 80%. Treatment response, as measured by minimal residual disease, has allowed us …

Advancement in the diagnosis and treatment of pedi-atric acute lymphoblastic leukemia
(ALL) is one of the greatest successes of modern medicine. Over the past 50 years, there …

Abstract Approximately 90% of the 2,000 children, adolescents, and young adults enrolled
each year in Children's Oncology Group acute lymphoblastic leukemia (ALL) trials will be …

Acute Lymphoblastic Leukemia in Children | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

Identification of biologically distinctive subsets of ALL through cytogenetic, molecular, and
gene expression studies, as well as investigations of minimal residual disease and host …

While the majority of children and adolescents with newly diagnosed childhood acute
lymphoblastic leukemia (ALL) will be cured, as many as 20% of patients will experience …

Purpose To review the impact of collaborative studies on advances in the biology and
treatment of acute lymphoblastic leukemia (ALL) in children and adolescents. Methods A …

The 50th anniversary of Seminars in Hematology coincides with the 50th anniversary of St.
Jude Children's Research Hospital, and both milestones are inexorably linked to studies …

The outcomes of pediatric acute lymphoblastic leukemia (ALL) have improved remarkably
during the last five decades. Such improvements were made possible by the incorporation of …