Mouse and human immune responses share neutralization epitopes of HAstV-VA1
Astroviruses are highly divergent and infect a wide variety of animal hosts. In 2009, a
genetically divergent human astrovirus (HAstV) strain VA1 was first identified in an outbreak …
genetically divergent human astrovirus (HAstV) strain VA1 was first identified in an outbreak …
Isolation of neutralizing monoclonal antibodies to human astrovirus and characterization of virus variants that escape neutralization
R Espinosa, T López, WA Bogdanoff… - Journal of …, 2019 - Am Soc Microbiol
Human astroviruses (HAstVs) cause severe diarrhea and represent an important health
problem in children under two years of age. Despite their medical importance, the study of …
problem in children under two years of age. Despite their medical importance, the study of …
Structural basis for escape of human astrovirus from antibody neutralization: broad implications for rational vaccine design
Human astroviruses are recognized as a leading cause of viral diarrhea worldwide in
children, immunocompromised patients, and the elderly. There are currently no vaccines …
children, immunocompromised patients, and the elderly. There are currently no vaccines …
Structure of a human astrovirus capsid-antibody complex and mechanistic insights into virus neutralization
WA Bogdanoff, J Campos, EI Perez, L Yin… - Journal of …, 2017 - Am Soc Microbiol
Human astroviruses (HAstVs) are a leading cause of viral diarrhea in young children, the
immunocompromised, and the elderly. There are no vaccines or antiviral therapies against …
immunocompromised, and the elderly. There are no vaccines or antiviral therapies against …
Human astroviruses: a tale of two strains
Since the 1970s, eight closely related serotypes of classical human astroviruses (HAstV)
have been associated with gastrointestinal illness worldwide. In the late 2000s, three …
have been associated with gastrointestinal illness worldwide. In the late 2000s, three …
Structure and antigenicity of the divergent human astrovirus VA1 capsid spike
Human astrovirus (HAstV) is a known cause of viral gastroenteritis in children worldwide, but
HAstV can cause also severe and systemic infections in immunocompromised patients …
HAstV can cause also severe and systemic infections in immunocompromised patients …
Human astrovirus capsid protein releases a membrane lytic peptide upon trypsin maturation
The human astrovirus (HAstV) is a non-enveloped, single-stranded RNA virus that is a
common cause of gastroenteritis. Most non-enveloped viruses use membrane disruption to …
common cause of gastroenteritis. Most non-enveloped viruses use membrane disruption to …
Molecular evolutionary analysis of type-1 human astroviruses identifies putative sites under selection pressure on the capsid protein
S De Grazia, G Lanave, F Bonura, N Urone… - Infection, Genetics and …, 2018 - Elsevier
Human astroviruses (HAstV) are important enteric pathogens that can be classified into eight
sero/genotypes (HAstV-1 to-8). Although the various HAstV types show global spread, type …
sero/genotypes (HAstV-1 to-8). Although the various HAstV types show global spread, type …
Structural, mechanistic, and antigenic characterization of the human astrovirus capsid
RL York, PA Yousefi, W Bogdanoff, S Haile… - Journal of …, 2016 - Am Soc Microbiol
Human astroviruses (HAstVs) are nonenveloped, positive-sense, single-stranded RNA
viruses that are a leading cause of viral gastroenteritis. HAstV particles display T= 3 …
viruses that are a leading cause of viral gastroenteritis. HAstV particles display T= 3 …
Biology and cellular tropism of a unique astrovirus strain: Murine astrovirus 2
SP Kelly, RJ Ricart Arbona, AO Michel… - Comparative …, 2021 - ingentaconnect.com
Murine astrovirus 2 (MuAstV2) is a novel murine astrovirus recently identified in laboratory
and wild mice. MuAstV2 readily transmits between immunocompetent mice yet fails to …
and wild mice. MuAstV2 readily transmits between immunocompetent mice yet fails to …