Preclinical models of epithelial ovarian cancer: practical considerations and challenges for a meaningful application
A Ciucci, M Buttarelli, A Fagotti, G Scambia… - Cellular and Molecular …, 2022 - Springer
Despite many improvements in ovarian cancer diagnosis and treatment, until now,
conventional chemotherapy and new biological drugs have not been shown to cure the …
conventional chemotherapy and new biological drugs have not been shown to cure the …
[HTML][HTML] Ovarian cancer: pathology, biology, and disease models
DG Rosen, G Yang, G Liu, I Mercado-Uribe… - … in bioscience: a …, 2009 - ncbi.nlm.nih.gov
Epithelial ovarian cancer, which comprises several histologic types and grades, is the most
lethal cancer among women in the United States. In this review, we summarize recent …
lethal cancer among women in the United States. In this review, we summarize recent …
Investigating the suitability of in vitro cell lines as models for the major subtypes of epithelial ovarian cancer
A McCabe, O Zaheed, SS McDade… - Frontiers in Cell and …, 2023 - frontiersin.org
Epithelial ovarian cancer (EOC) is the most fatal gynaecological malignancy, accounting for
over 200,000 deaths worldwide per year. EOC is a highly heterogeneous disease, classified …
over 200,000 deaths worldwide per year. EOC is a highly heterogeneous disease, classified …
[HTML][HTML] The promise and challenge of ovarian cancer models
N Hasan, AW Ohman, DM Dinulescu - Translational cancer …, 2015 - ncbi.nlm.nih.gov
The complexity and heterogeneity of ovarian cancer cases are difficult to reproduce in in
vitro studies, which cannot adequately elucidate the molecular events involved in tumor …
vitro studies, which cannot adequately elucidate the molecular events involved in tumor …
Current status and evolution of preclinical drug development models of epithelial ovarian cancer
PA Konstantinopoulos, UA Matulonis - Frontiers in oncology, 2013 - frontiersin.org
Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy and the fifth most
common cause of female cancer death in the United States. Although important advances in …
common cause of female cancer death in the United States. Although important advances in …
Revisiting ovarian cancer preclinical models: implications for a better management of the disease
Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy. Despite progress
in identifying “hallmark” genetic alterations associated with the main subtypes of epithelial …
in identifying “hallmark” genetic alterations associated with the main subtypes of epithelial …
Molecular pathogenesis and therapeutic targets in epithelial ovarian cancer
JR Chien, G Aletti, DA Bell, GL Keeney… - Journal of cellular …, 2007 - Wiley Online Library
Ovarian cancer, the most aggressive gynecologic cancer, is the foremost cause of death
from gynecologic malignancies in the developed world. Two primary reasons explain its …
from gynecologic malignancies in the developed world. Two primary reasons explain its …
Ovarian cancer update: lessons from morphology, molecules, and mice
KR Cho - Archives of pathology & laboratory medicine, 2009 - meridian.allenpress.com
Ovarian carcinomas are a heterogeneous group of neoplasms. Pathologists currently
employ a morphology-based classification system to divide ovarian carcinomas into major …
employ a morphology-based classification system to divide ovarian carcinomas into major …
Molecular characterization of epithelial ovarian cancer: implications for diagnosis and treatment
V Rojas, KM Hirshfield, S Ganesan… - International journal of …, 2016 - mdpi.com
Epithelial ovarian cancer is a highly heterogeneous disease characterized by multiple
histological subtypes. Molecular diversity has been shown to occur within specific …
histological subtypes. Molecular diversity has been shown to occur within specific …