5-HT and the immune system
GP Ahern - Current opinion in pharmacology, 2011 - Elsevier
The classical neurotransmitter, serotonin (5-HT), plays an important role outside of the
central nervous system in immune signaling. Here I review recent studies describing 5-HT …
central nervous system in immune signaling. Here I review recent studies describing 5-HT …
Role of serotonin in the immune system and in neuroimmune interactions
R Mössner, KP Lesch - Brain, behavior, and immunity, 1998 - Elsevier
Serotonin (5-HT) is one of the most extensively studied neurotransmitters of the central
nervous system. 5-HT is, however, also present in a variety of peripheral tissues including in …
nervous system. 5-HT is, however, also present in a variety of peripheral tissues including in …
Serotonin upregulates mitogen-stimulated b lymphocyte proliferation through 5-HT1Areceptors
K Iken, S Chheng, A Fargin, AC Goulet, E Kouassi - Cellular immunology, 1995 - Elsevier
Serotonin is a well-known neurotransmitter and neuroimmunomodulator which has been
reported to modulate T cell and NK cell proliferation. In this study we investigated whether …
reported to modulate T cell and NK cell proliferation. In this study we investigated whether …
5-HT1B receptors play a prominent role in the proliferation of T-lymphocytes
J Yin, RH Albert, AP Tretiakova, BA Jameson - Journal of …, 2006 - Elsevier
Serotonin plays a role in T cell activation, but there is no clear consensus of which of the 14
serotonergic receptors control this activations pathway. We have used a broad range of …
serotonergic receptors control this activations pathway. We have used a broad range of …
Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor
M León-Ponte, GP Ahern, PJ O'Connell - Blood, 2007 - ashpublications.org
Although typically considered a neurotransmitter, there is substantial evidence that serotonin
(5-HT) plays an important role in the pathogenesis of inflammatory disorders. Despite these …
(5-HT) plays an important role in the pathogenesis of inflammatory disorders. Despite these …
mRNA expression of serotonin receptors in cells of the immune tissues of the rat
J Stefulj, B Jernej, L Cicin-Sain, I Rinner… - Brain, behavior, and …, 2000 - Elsevier
Serotonin (5-hydroxytryptamine, 5-HT) has been shown to play a role in immunoregulation;
however, little is known about specific subtypes of 5-HT receptors involved in peripheral …
however, little is known about specific subtypes of 5-HT receptors involved in peripheral …
Regulation of antigen-specific CTL and Th1 cell activation through 5-Hydroxytryptamine 2A receptor
M Inoue, T Okazaki, T Kitazono, M Mizushima… - International …, 2011 - Elsevier
Serotonin (5-Hydroxytryptamine, 5-HT) is one of the most extensively studied
neurotransmitters in the central nervous system. Also expressed in peripheral tissues, 5-HT …
neurotransmitters in the central nervous system. Also expressed in peripheral tissues, 5-HT …
[HTML][HTML] Role of 5-HT7 receptors in the immune system in health and disease
A Quintero-Villegas, SI Valdés-Ferrer - Molecular Medicine, 2020 - Springer
Abstract In mammalians, serotonin (5-HT) has critical roles in the central nervous system
(CNS), including mood stability, pain tolerance, or sleep patterns. However, the vast majority …
(CNS), including mood stability, pain tolerance, or sleep patterns. However, the vast majority …
A novel form of immune signaling revealed by transmission of the inflammatory mediator serotonin between dendritic cells and T cells
PJ O'Connell, X Wang, M Leon-Ponte, C Griffiths… - Blood, 2006 - ashpublications.org
Adaptive immunity is triggered at the immune synapse, where peptide-major
histocompatibility complexes and costimulatory molecules expressed by dendritic cells …
histocompatibility complexes and costimulatory molecules expressed by dendritic cells …
Immunomodulatory effects mediated by serotonin
R Arreola, E Becerril-Villanueva… - Journal of …, 2015 - Wiley Online Library
Serotonin (5‐HT) induces concentration‐dependent metabolic effects in diverse cell types,
including neurons, entherochromaffin cells, adipocytes, pancreatic beta‐cells, fibroblasts …
including neurons, entherochromaffin cells, adipocytes, pancreatic beta‐cells, fibroblasts …