[HTML][HTML] Necroptosis in the pathophysiology of disease

MK Khoury, K Gupta, SR Franco, B Liu - The American journal of pathology, 2020 - Elsevier
Over the past 15 years, elegant studies have demonstrated that in certain conditions,
programed cell death resembles necrosis and depends on a unique molecular pathway with …

Necroptosis

A Linkermann, DR Green - New England Journal of Medicine, 2014 - Mass Medical Soc
Necroptosis | NEJM Skip to main content NEJM Group Follow Us Facebook Twitter Instagram
YouTube LinkedIn Prepare to become a physician, build your knowledge, lead a health care …

Necroptosis: mechanisms and relevance to disease

L Galluzzi, O Kepp, FKM Chan… - Annual Review of …, 2017 - annualreviews.org
Necroptosis is a form of regulated cell death that critically depends on receptor-interacting
serine-threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like (MLKL) and …

[HTML][HTML] The double-edged functions of necroptosis

K Ye, Z Chen, Y Xu - Cell Death & Disease, 2023 - nature.com
Necroptosis refers to a regulated form of cell death induced by a variety of stimuli. Although it
has been implicated in the pathogenesis of many diseases, there is evidence to support that …

The mechanism of necroptosis in normal and cancer cells

S Fulda - Cancer biology & therapy, 2013 - Taylor & Francis
Programmed cell death is a basic cellular process that is critical to maintain tissue
homeostasis. Besides apoptosis, necroptosis has more recently been discovered as another …

Necroptosis: a novel cell death modality and its potential relevance for critical care medicine

G Moreno-Gonzalez, P Vandenabeele… - American journal of …, 2016 - atsjournals.org
Cell death is intertwined with life in development, homeostasis, pathology, and aging. Until
recently, apoptosis was the best known form of programmed cell death, whereas necrosis …

[HTML][HTML] Current translational potential and underlying molecular mechanisms of necroptosis

T Molnár, A Mázló, V Tslaf, AG Szöllősi, G Emri… - Cell death & …, 2019 - nature.com
Cell death has a fundamental impact on the evolution of degenerative disorders,
autoimmune processes, inflammatory diseases, tumor formation and immune surveillance …

Necroptotic cell death in anti‐cancer therapy

O Krysko, TL Aaes, VE Kagan, K D'Herde… - Immunological …, 2017 - Wiley Online Library
Necroptosis is one the best‐characterized forms of regulated necrosis. Necroptosis is
mediated by the kinase activities of receptor interacting protein kinase‐1 and receptor …

Programmed necrosis: from molecules to health and disease

L Galluzzi, TV Berghe, N Vanlangenakker… - International review of …, 2011 - Elsevier
During the past decade, cell death researchers have witnessed a gradual but deep
conceptual revolution: it has been unequivocally shown that necrosis, which for long had …

Therapeutic exploitation of necroptosis for cancer therapy

S Fulda - Seminars in cell & developmental biology, 2014 - Elsevier
Evasion of programmed cell death represents one of the hallmarks of cancers that
contributes to tumor initiation, progression and treatment resistance. This calls for novel …