The impact of dysregulated microRNA biogenesis machinery and microRNA sorting on neurodegenerative diseases

YT Weng, YM Chang, Y Chern - International Journal of Molecular …, 2023 - mdpi.com
MicroRNAs (miRNAs) are 22-nucleotide noncoding RNAs involved in the differentiation,
development, and function of cells in the body by targeting the 3′-untranslated regions …

Noncoding RNAs in neurodegenerative diseases

SD Rege, T Geetha, SR Pondugula… - International …, 2013 - Wiley Online Library
Noncoding RNAs are widely known for their various essential roles in the development of
central nervous system. It involves neurogenesis, neural stem cells generation, maintenance …

Interplay of RNA-binding proteins and microRNAs in neurodegenerative diseases

C Kinoshita, N Kubota, K Aoyama - International Journal of Molecular …, 2021 - mdpi.com
The number of patients with neurodegenerative diseases (NDs) is increasing, along with the
growing number of older adults. This escalation threatens to create a medical and social …

MicroRNA alteration, application as biomarkers, and therapeutic approaches in neurodegenerative diseases

TPN Nguyen, M Kumar, E Fedele, G Bonanno… - International journal of …, 2022 - mdpi.com
MicroRNAs (miRNAs) are essential post-transcriptional gene regulators involved in various
neuronal and non-neuronal cell functions and play a key role in pathological conditions …

Mechanism and Therapeutic Prospect of miRNAs in Neurodegenerative Diseases

YM Ma, L Zhao - Behavioural Neurology, 2023 - Wiley Online Library
MicroRNAs (miRNAs) are the smallest class of noncoding RNAs, which widely exist in
animals and plants. They can inhibit translation or overexpression by combining with mRNA …

[HTML][HTML] Macro roles for microRNAs in neurodegenerative diseases

D Rajgor - Non-Coding RNA Research, 2018 - Elsevier
Neurodegenerative diseases (NDs) are typically adult-onset progressive disorders that
perturb neuronal function, plasticity and health that arise through a host of one or more …

MicroRNAs dysregulation and mitochondrial dysfunction in neurodegenerative diseases

M Catanesi, M d'Angelo, MG Tupone… - International Journal of …, 2020 - mdpi.com
Neurodegenerative diseases are debilitating and currently incurable conditions causing
severe cognitive and motor impairments, defined by the progressive deterioration of …

The involvement of microRNAs in neurodegenerative diseases

S Maciotta, M Meregalli, Y Torrente - Frontiers in cellular …, 2013 - frontiersin.org
Neurodegenerative diseases (NDDs) originate from a loss of neurons in the central nervous
system and are severely debilitating. The incidence of NDDs increases with age, and they …

Causes and consequences of microRNA dysregulation in neurodegenerative diseases

L Tan, JT Yu, L Tan - Molecular neurobiology, 2015 - Springer
Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD),
Huntington's disease (HD) and amyotrophic lateral sclerosis (ALS), originate from a loss of …

The role of microRNAs in the pathophysiology of human central nervous system: a focus on neurodegenerative diseases

D Rezaee, F Saadatpour, N Akbari, A Zoghi… - Ageing Research …, 2023 - Elsevier
Abstract microRNAs (miRNAs) are suggested to play substantial roles in regulating the
development and various physiologic functions of the central nervous system (CNS). These …