Identification of novel prognostic targets in coronary artery disease and related complications using bioinformatics and next generation sequencing data analysis

B Vastrad, C Vastrad - bioRxiv, 2023 - biorxiv.org
Coronary artery disease (CAD) is the most common cardiovascular disorder and the leading
cause of heart-related deaths in world. Increasing molecular targets have been discovered …

Identification and Interaction Analysis of Molecular Markers in Myocardial Infarction by Integrated Bioinformatics Analysis

B Vastrad, C Vastrad - bioRxiv, 2021 - biorxiv.org
Myocardial infarction (MI) is the leading cardiovascular diseases in worldwide, yet relatively
little is known about the genes and signaling pathways involved in MI progression. The …

[HTML][HTML] Weighted gene coexpression network analysis identifies crucial genes involved in coronary atherosclerotic heart disease

J Bao - Disease Markers, 2022 - hindawi.com
Background. Coronary atherosclerotic heart disease (CHD) is a lethal disease with an
unstated pathogenic mechanism. Therefore, it is urgent to develop innovative strategies to …

Screening hub genes in coronary artery disease based on integrated analysis

F Long, L Wang, L Yang, Z Ji, YG Hu - Cardiology Journal, 2018 - journals.viamedica.pl
Background: Coronary artery disease (CAD) is the leading cause of mortality worldwide.
Identifying key pathogenic genes benefits the understanding molecular mechanism of CAD …

[HTML][HTML] Identification of hub biomarkers of myocardial infarction by single-cell sequencing, bioinformatics, and machine learning

Q Zhang, Y Guo, B Zhang, H Liu, Y Peng… - Frontiers in …, 2022 - frontiersin.org
Background: Myocardial infarction (MI) is one of the first cardiovascular endangering human
health. Inflammatory response plays a significant role in the pathophysiological process of …

[HTML][HTML] Bioinformatics analysis reveals diagnostic markers and vital pathways involved in acute coronary syndrome

M Li, C Ren, C Wu, X Li, X Li, W Mao - Cardiology Research and …, 2020 - hindawi.com
Background. Acute coronary syndrome (ACS) has a high incidence and mortality rate. Early
detection and intervention would provide clinical benefits. This study aimed to reveal hub …

Transcriptome signatures reveal candidate key genes in the peripheral blood mononuclear cells of patients with coronary artery disease and prediction of small drug …

V Kolur, B Vastrad, A Tengli, C Vastrad, I Kotturshetti - 2020 - researchsquare.com
Coronary artery disease (CAD) is one of the most common disorders in the cardiovascular
system. This study aims to explore potential signaling pathways and important biomarkers …

Bioinformatics analysis identifies potential diagnostic signatures for coronary artery disease

D Zhang, L Guan, X Li - Journal of International Medical …, 2020 - journals.sagepub.com
Background Coronary artery disease (CAD) is the leading cause of mortality worldwide. We
aimed to screen out potential gene signatures and construct a diagnostic model for CAD …

Roles of Immune and Oxidative Stress-Related Factors in the Diagnosis of Coronary Artery Disease: A Retrospective Study

Y Shu, Y Zheng, Y Guo, D Zhu… - The Heart Surgery …, 2023 - journal.hsforum.com
Background: Coronary artery disease (CAD) is one of the main causes of sudden death, but
its exact pathogenesis requires further study. Thus, this study aimed to explore the immune …

[HTML][HTML] The identification and validation of hub genes associated with acute myocardial infarction using weighted gene co-expression network analysis

J Xue, L Chen, H Cheng, X Song, Y Shi, L Li… - Journal of …, 2022 - mdpi.com
Acute myocardial infarction (AMI), one of the most severe and fatal cardiovascular diseases,
remains the main cause of mortality and morbidity worldwide. The objective of this study is to …