[PDF][PDF] Curcumin lessens unpredictable chronic mild stress-induced depression and memory deficits by modulating oxidative stress and cholinergic activity

F Naqvi, S Saleem, F Naqvi, Z Batool, S Sadir… - Pak J Pharm …, 2019 - academia.edu
Unpredictable chronic mild stress (UCMS) model is the most established method to study
neurobiological mechanisms of depression. This work was intended to explore the efficacy …

Pretreatment with curcumin attenuates anxiety while strengthens memory performance after one short stress experience in male rats

S Haider, F Naqvi, Z Batool, S Tabassum, S Sadir… - Brain research …, 2015 - Elsevier
It is observed that memories are more strengthened in a stressful condition. Studies have
also demonstrated an association between stressful events and the onset of depression and …

Piperine potentiates the protective effects of curcumin against chronic unpredictable stress-induced cognitive impairment and oxidative damage in mice

P Rinwa, A Kumar - Brain research, 2012 - Elsevier
Life event stressors are the major vulnerability factors for the development of cognitive
disorders. A vital therapeutic for stress related disorders is curcumin, derived from curry …

Adaptogenic potential of curcumin in experimental chronic stress and chronic unpredictable stress-induced memory deficits and alterations in functional homeostasis

N Bhatia, AS Jaggi, N Singh, P Anand… - Journal of natural …, 2011 - Springer
The present study was designed to investigate the role of curcumin in chronic stress and
chronic unpredictable stress-induced memory deficits and alteration of functional …

Effects of curcumin on learning and memory deficits, BDNF, and ERK protein expression in rats exposed to chronic unpredictable stress

D Liu, Z Wang, Z Gao, K Xie, Q Zhang, H Jiang… - Behavioural brain …, 2014 - Elsevier
Accumulating evidence suggests that cognitive processes, such as learning and memory,
are affected in depression and antidepressant treatment may ameliorate cognitive …

Adaptogenic effects of curcumin on depression induced by moderate and unpredictable chronic stress in mice

JG da Silva Marques, FTT Antunes… - Behavioural brain …, 2021 - Elsevier
Curcumin has been investigated for the prevention and treatment of diseases due to its anti-
oxidant, anti-inflammatory, immunomodulatory, and neuroprotective actions. This current …

Curcumin attenuates chronic unpredictable mild stress‐induced depressive‐like behaviors via restoring changes in oxidative stress and the activation of Nrf2 …

D Liao, C Lv, L Cao, D Yao, Y Wu… - Oxidative Medicine …, 2020 - Wiley Online Library
Accumulating evidence has demonstrated that oxidative stress is associated with
depression. Our present study aimed at investigating the antidepressant effect and the …

Anti-depressant like effect of curcumin and its combination with piperine in unpredictable chronic stress-induced behavioral, biochemical and neurochemical changes

MK Bhutani, M Bishnoi, SK Kulkarni - Pharmacology Biochemistry and …, 2009 - Elsevier
Curcumin, a yellow pigment extracted from rhizomes of the plant Curcuma longa (turmeric),
has been widely used as food additive and also as a herbal medicine throughout Asia. The …

Antidepressant-like effects of curcumin in chronic mild stress of rats: involvement of its anti-inflammatory action

H Jiang, Z Wang, Y Wang, K Xie, Q Zhang… - Progress in Neuro …, 2013 - Elsevier
Mounting evidence suggests that inflammation may contribute to the pathophysiology of
depression. Curcumin, a polyphenol extracted from the plant Curcuma longa, exhibits a …

Investigation of antistress and antidepressant activities of synthetic curcumin analogues: Behavioral and biomarker approach

H Hussain, S Ahmad, SWA Shah, A Ullah… - Biomedicines, 2022 - mdpi.com
Depression is a serious psychiatric disorder that affects millions of individuals all over the
world, thus demanding special attention from researchers in order to investigate its effective …