In recent years, poorly water-soluble drug candidates in the drug development pipeline have
been a challenging issue for the pharmaceutical industry. Many delivery systems, such as …

One of the most important parameters in pharmacy is drug solubility. Solubility affects the
efficacy of a drug. Drug solubility has an important role in determining the concentration of a …

A drug's aqueous solubility is defined as the ability to dissolve in a particular solvent, and it
is currently a major hurdle in bringing new drug molecules to the market. According to some …

Solid dispersions are one of the most promising strategies to improve the oral bioavailability
of poorly water soluble drugs. By reducing drug particle size to the absolute minimum, and …

The solubility behavior of drugs remains one of the most exigent aspects in formulation
development. With the advent of combinatorial chemistry and high throughput screening, the …

The solubility behavior of drugs remains one of the most challenging aspects in the
formulation development. Although there was a great interest in solid dispersion systems …

Low water solubility is the main hindrance in the growth of pharmaceutical industry.
Approximately 90% of newer molecules under investigation for drugs and 40% of novel …

The solubility behavior of drugs remains one of the most exigent aspects in formulation
development. With the advent of combinatorial chemistry and high throughput screening, the …

In recent years, the formulation of poorly soluble compounds presented interesting
challenges for formulation scientists in the pharmaceutical industry. Up to 40% of new …

The low water solubility of pharmacoactive molecules limits their pharmacological potential,
but the solubility parameter cannot compromise, and so different approaches are employed …