Graph theoretical measures of fast ripples support the epileptic network hypothesis
The epileptic network hypothesis and epileptogenic zone hypothesis are two theories of
ictogenesis. The network hypothesis posits that coordinated activity among interconnected …
ictogenesis. The network hypothesis posits that coordinated activity among interconnected …
Increased gamma and decreased fast ripple connections of epileptic tissue: A high‐frequency directed network approach
WJEM Zweiphenning, HM Keijzer, E van Diessen… - …, 2019 - Wiley Online Library
Objective New insights into high‐frequency electroencephalographic activity and network
analysis provide potential tools to improve delineation of epileptic tissue and increase the …
analysis provide potential tools to improve delineation of epileptic tissue and increase the …
Graph analysis of epileptogenic networks in human partial epilepsy
Purpose: The current gold standard for the localization of the cortical regions responsible for
the initiation and propagation of the ictal activity is through the use of invasive …
the initiation and propagation of the ictal activity is through the use of invasive …
Local neuronal excitation and global inhibition during epileptic fast ripples in humans
Understanding the neuronal basis of epileptic activity is a major challenge in neurology.
Cellular integration into larger scale networks is all the more challenging. In the local field …
Cellular integration into larger scale networks is all the more challenging. In the local field …
Ictal propagation of high frequency activity is recapitulated in interictal recordings: effective connectivity of epileptogenic networks recorded with intracranial EEG
Seizures are increasingly understood to arise from epileptogenic networks across which
ictal activity is propagated and sustained. In patients undergoing invasive monitoring for …
ictal activity is propagated and sustained. In patients undergoing invasive monitoring for …
[HTML][HTML] Graph theoretical measures of fast ripple networks improve the accuracy of post-operative seizure outcome prediction
Fast ripples (FR) are a biomarker of epileptogenic brain, but when larger portions of FR
generating regions are resected seizure freedom is not always achieved. To evaluate and …
generating regions are resected seizure freedom is not always achieved. To evaluate and …
[HTML][HTML] Dynamic network properties of the interictal brain determine whether seizures appear focal or generalised
Current explanatory concepts suggest seizures emerge from ongoing dynamics of brain
networks. It is unclear how brain network properties determine focal or generalised seizure …
networks. It is unclear how brain network properties determine focal or generalised seizure …
Interictal spike connectivity in human epileptic neocortex
B Maharathi, R Wlodarski, S Bagla, E Asano… - Clinical …, 2019 - Elsevier
Objective Interictal spikes are a biomarker of epilepsy, yet their precise roles are poorly
understood. Using long-term neocortical recordings from epileptic patients, we investigated …
understood. Using long-term neocortical recordings from epileptic patients, we investigated …
A candidate mechanism underlying the variance of interictal spike propagation
HR Sabolek, WB Swiercz, KP Lillis… - Journal of …, 2012 - Soc Neuroscience
Synchronous activation of neural networks is an important physiological mechanism, and
dysregulation of synchrony forms the basis of epilepsy. We analyzed the propagation of …
dysregulation of synchrony forms the basis of epilepsy. We analyzed the propagation of …
Epileptic seizures from abnormal networks: Why some seizures defy predictability
Seizure prediction has proven to be difficult in clinically realistic environments. Is it possible
that fluctuations in cortical firing could influence the onset of seizures in an ictal zone? To …
that fluctuations in cortical firing could influence the onset of seizures in an ictal zone? To …