Intermittent hypoxia (IH) is a major clinical feature of obstructive sleep apnea (OSA). The
mechanisms that become dysregulated after periods of exposure to IH are unclear …

Obstructive sleep apnea (OSA) results from episodes of airway collapse and intermittent
hypoxia (IH) and is associated with a host of health complications. Although the lung is the …

Obstructive sleep apnea (OSA) is a complex process that can lead to the dysregulation of
the molecular clock, as well as 24 h rhythms of sleep and wake, blood pressure, and other …

The occurrence and sequelae of disorders that lead to hypoxic spells such as asthma,
chronic obstructive pulmonary disease, and obstructive sleep apnea (OSA) exhibit daily …

Obstructive sleep apnea (OSA) is a chronic condition characterized by recurrent pauses in
breathing caused by the collapse of the upper airways, which results in intermittent hypoxia …

Objective To review the effects of the circadian clock on homeostasis, the functional
interaction between the circadian clock and hypoxia-inducible factors, and the role of …

At least one-third of adults in the United States experience intermittent hypoxia (IH) due to
health or living conditions. The majority of these adults suffer with sleep breathing conditions …

Obstructive sleep apnea (OSA) is common and linked to a variety of poor health outcomes. A
key modulator of this disease is nocturnal intermittent hypoxia. There is striking …

ABSTRACT Obstructive Sleep Apnea (OSA) is a common disorder that is associated with
disability, premature mortality and lost quality of life. Excessive daytime sleepiness and …

AIMS: Obstructive sleep apnea syndrome (OSAS), characterized by intermittent
hypoxia/reoxygenation (IHR), is often associated with changing levels of circulating …