Cytomegalovirus (CMV) virus load kinetics to predict recurrent disease in solid-organ transplant patients with CMV disease

A Humar, D Kumar, G Boivin… - The Journal of infectious …, 2002 - academic.oup.com
Despite standard therapy, cytomegalovirus (CMV) disease recurs in a significant proportion
of organ transplant recipients. The kinetics of CMV load in response to therapy may allow …

Cytomegalovirus (CMV) DNA load predicts relapsing CMV infection after solid organ transplantation

IG Sia, JA Wilson, CM Groettum, MJ Espy… - The Journal of …, 2000 - academic.oup.com
Cytomegalovirus (CMV) DNA load was analyzed as a marker for relapse of CMV infection in
24 solid organ transplant patients with CMV infection or disease who received a fixed 14 …

Prediction of recurrent cytomegalovirus disease after treatment with ganciclovir in solid-organ transplant recipients

AP VAN DEN BERG, WJ VAN SON… - …, 1993 - journals.lww.com
CMV disease often recurs after initially successful antiviral therapy. We retrospectively
determined in a group of 36 organ transplant patients whether clinical, virological, or …

Application of viral-load kinetics to identify patients who develop cytomegalovirus disease after transplantation

VC Emery, CA Sabin, AV Cope, D Gor… - The Lancet, 2000 - thelancet.com
Background Cytomegalovirus (CMV) continues to be a major problem post-transplantation;
early markers for predicting patients at risk of CMV disease are needed. Peak CMV load in …

Kinetics of cytomegalovirus load decrease in solid-organ transplant recipients after preemptive therapy with valganciclovir

FM Mattes, EG Hainsworth, AFH Walker… - The Journal of …, 2005 - academic.oup.com
The availability of valganciclovir (VGCV) has significantly simplified the treatment of human
cytomegalovirus (HCMV) infection after solid-organ transplantation. We show that there was …

Recurrence of CMV infection and the effect of prolonged antivirals in organ transplant recipients

Y Natori, A Humar, S Husain, C Rotstein… - …, 2017 - journals.lww.com
Background Although initial therapy for cytomegalovirus (CMV) is usually successful, a
significant subset of patients may have recurrent viremia. However, the epidemiology and …

Dynamics of cytomegalovirus replication during preemptive therapy with oral ganciclovir

RR Razonable, H Van Cruijsen… - The Journal of …, 2003 - academic.oup.com
The degree and dynamics of cytomegalovirus (CMV) replication were investigated in blood
samples that were prospectively collected in the context of a placebo-controlled study …

Prevention dof recurrent cytomegalovirus disease in renal and liver transplant recipients: effect of oral ganciclovir

N Turgeon, JA Fishman, M Doran… - Transplant Infectious …, 2000 - Wiley Online Library
Background: Although the primary treatment of symptomatic cytomegalovirus (CMV) disease
in organ transplant recipients is successful in> 90% of individuals, relapsing disease …

[HTML][HTML] Clinical utility of cytomegalovirus viral load testing for predicting CMV disease in D+/R-solid organ transplant recipients

A Humar, C Paya, MD Pescovitz, E Dominguez… - American Journal of …, 2004 - Elsevier
Despite prophylaxis, cytomegalovirus (CMV) disease is common in donor seropositive
(D+)/recipient seronegative (R-) transplant patients after cessation of prophylaxis. Early …

Clinical and epidemiological predictors of recurrent cytomegalovirus disease in orthotopic liver transplant recipients

ME Falagas, DR Snydman, J Griffith… - Clinical infectious …, 1997 - academic.oup.com
Predictors of recurrent cytomegalovirus (CMV) disease after the first episode of successfully
treated CMV disease in orthotopic liver transplant recipients were studied. Recurrent CMV …