Osteosarcoma (OS) is the most common primary bone sarcoma affecting the life of pediatric
patients. The clinical treatment faces numerous difficulties, including the adverse effects of …

Results Our data suggested that Res blocks cell proliferation, migration, and invasion, and
activates apoptotic cell death in osteosarcoma MG-63 cells. We found that Res potentially …

The chemopreventive activity of resveratrol (RSVL) has been demonstrated in several types
of cancer. However, its effects and the underling mechanisms remain poorly understood. In …

The aim of the current study was to investigate the effects of resveratrol (Res) on vascular
endothelial growth factor (VEGF) expression and cell proliferation in the human …

Bone cancer is a malignant primary tumour of the bone with different typing, such as,
osteosarcoma, chondrosarcoma, Ewing's sarcoma and fibrosarcoma. Despite the clinical …

Osteosarcoma is a high-grade bone sarcoma with strong invasive ability. However,
treatment with traditional chemotherapeutic drugs is limited by low tolerability and side …

Cancer remains to be an unresolved medical challenge despite of tremendous
advancement in basic science research and clinical medicine. One of the major limitations is …

Multiple myeloma is characterized by the accumulation of clonal malignant plasma cells in
the bone marrow, which stimulates bone destruction by osteoclasts and reduces bone …

Rhabdomysarcoma is the most common soft tissue tumour in children under the age of 15.
Although the introduction of multimodal treatment programmes, including chemotherapy …

Resveratrol shows potent anti-tumor therapeutic properties in various tumors. However, the
exact effect of resveratrol on osteosarcoma cells, especially cancer stem cells, remains …