Lung injury after one-lung ventilation: a review of the pathophysiologic mechanisms affecting the ventilated and the collapsed lung

J Lohser, P Slinger - Anesthesia & Analgesia, 2015 - journals.lww.com
Lung injury is the leading cause of death after thoracic surgery. Initially recognized after
pneumonectomy, it has since been described after any period of 1-lung ventilation (OLV) …

Lung injury after thoracic surgery and one-lung ventilation

J Gothard - Current Opinion in Anesthesiology, 2006 - journals.lww.com
Pulmonary damage in the form of acute lung injury and adult respiratory distress syndrome
is a major cause of morbidity and mortality after thoracic surgery. An understanding of the …

[HTML][HTML] One-lung ventilation: for how long?

C Tekinbas, H Ulusoy, E Yulug, MM Erol, A Alver… - The Journal of thoracic …, 2007 - Elsevier
OBJECTIVE: Lung injury induced by one-lung ventilation is rare, but it is a condition that may
result in high mortality. This study evaluates the effects of one-lung ventilation and occlusion …

Acute lung injury in thoracic surgery

G Della Rocca, C Coccia - Current Opinion in Anesthesiology, 2013 - journals.lww.com
The goal of ventilation is to minimize lung trauma by avoiding overdistension and repetitive
alveolar collapse, while providing adequate oxygenation. Protective ventilation is not simply …

One-lung ventilation with high tidal volumes and zero positive end-expiratory pressure is injurious in the isolated rabbit lung model

MG de Abreu, M Heintz, A Heller… - Anesthesia & …, 2003 - journals.lww.com
We tested the hypothesis that one-lung ventilation (OLV) with high tidal volumes (Vt) and
zero positive end-expiratory pressure (PEEP) may lead to ventilator-induced lung injury. In …

Mechanisms of ventilator-induced lung injury in healthy lungs

PL Silva, D Negrini, PRM Rocco - Best Practice & Research Clinical …, 2015 - Elsevier
Mechanical ventilation is an essential method of patient support, but it may induce lung
damage, leading to ventilator-induced lung injury (VILI). VILI is the result of a complex …

Pro: low tidal volume is indicated during one-lung ventilation

P Slinger - Anesthesia & Analgesia, 2006 - journals.lww.com
Since the introduction of one-lung ventilation (OLV) as a standard practice during thoracic
surgery in the first half of the last century, anesthesiologists have had to deal with the …

Evidence-based management of one-lung ventilation

J Lohser - Anesthesiology clinics, 2008 - Elsevier
One-lung ventilation (OLV) is essential for many thoracic and an increasing number of non-
thoracic minimally invasive procedures. Beyond the well-recognized disturbance of …

Management of one-lung ventilation: impact of tidal volume on complications after thoracic surgery

RS Blank, DA Colquhoun, ME Durieux… - …, 2016 - pubs.asahq.org
Background The use of lung-protective ventilation (LPV) strategies may minimize iatrogenic
lung injury in surgical patients. However, the identification of an ideal LPV strategy …

Ventilator-induced lung injury: the anatomical and physiological framework

L Gattinoni, A Protti, P Caironi, E Carlesso - Critical care medicine, 2010 - journals.lww.com
Since its introduction into the management of the acute respiratory distress syndrome,
mechanical ventilation has been so strongly interwoven with its side effects that it came to be …