Protein serine/threonine phosphatase 2A (PP2A) regulates diverse cellular processes via
the formation of~ 100 heterotrimeric holoenzymes. However, a scarcity of knowledge on …

Abstract Protein phosphatase 2A (PP2A) inactivation is common in cancer, leading to
sustained activation of pro-survival and growth-promoting pathways. PP2A consists of a …

Members of the B′/B56/PR61 family regulatory subunits of PP2A determine the subcellular
localization, substrate specificity, and catalytic activity of PP2A in a wide range of biological …

An increasing number of mutations associated with devastating human diseases are
diagnosed by whole-genome/exon sequencing. Recurrent de novo missense mutations …

PP2A is a highly conserved eukaryotic serine/threonine protein phosphatase of the PPP
family of phosphatases with fundamental cellular functions. In cells, PP2A targets specific …

Dynamic protein phosphorylation is a fundamental mechanism regulating biological
processes in all organisms. Protein phosphatase 2A (PP2A) is the main source of …

Abstract Protein phosphatase 2A (PP2A) is a family of heterotrimeric protein phosphatases
that has a multitude of functions inside the cell, acting through various substrate targets in …

Protein phosphorylation is a post-translational modification essential for the control of the
activity of most enzymes in the cell. This protein modification results from a fine-tuned …

PP2A is a major serine/threonine phosphatase class involved in the regulation of cell
signaling through the removal of protein phosphorylation. This class of phosphatases is …

Protein serine/threonine phosphatase 2A (PP2A) is a major cellular enzyme implicated in
the control of a wide variety of biological processes. The predominant form of PP2A in cells …