Penile intraepithelial neoplasia: Distribution of subtypes, HPV genotypes and p16INK4a in 84 international cases

MJ Fernández-Nestosa, O Clavero, DF Sánchez… - Human Pathology, 2023 - Elsevier
There are few pathologic or molecular studies of penile precancerous lesions, and the
majority refers to lesions associated with invasive carcinomas. Penile Intraepithelial …

[HTML][HTML] Pathological characterization and clinical outcome of penile intraepithelial neoplasia variants: a North American series

MMS Hogan, AJ Spieker, M Orejudos, T Gheit, M Herfs… - Modern Pathology, 2022 - Elsevier
Penile intraepithelial neoplasia (PeIN) is classified as human papillomavirus (HPV)-and non-
HPV-related. This classification is associated with distinct morphologic subtypes. The natural …

Comparison of human papillomavirus genotypes in penile intraepithelial neoplasia and associated lesions: LCM-PCR study of 87 lesions in 8 patients

MJ Fernández-Nestosa, N Guimerà… - … Journal of Surgical …, 2020 - journals.sagepub.com
Penile intraepithelial neoplasia (PeIN) is currently classified in human papillomavirus (HPV)-
and non-HPV-related subtypes with variable HPV genotypes. PeINs are frequently …

Identification and genotyping of human papillomavirus in a Spanish cohort of penile squamous cell carcinomas: correlation with pathologic subtypes, p16INK4a …

C Ferrándiz-Pulido, E Masferrer, I De Torres… - Journal of the American …, 2013 - Elsevier
BACKGROUND: Penile squamous cell carcinoma (PSCC) is a tumor with a high metastatic
potential. In PSCC the attributable fraction to human papillomavirus (HPV) is not well …

Updates in the pathology of penile intraepithelial neoplasia

GA Giannico, AL Cubilla - Diagnostic Histopathology, 2023 - Elsevier
Penile intraepithelial neoplasia (PeIN) is the putative histologic precursor of penile
squamous cell carcinoma. PeIN is classified into HPV-associated and HPV-independent …

Distinctive immunohistochemical profile of penile intraepithelial lesions: a study of 74 cases

A Chaux, R Pfannl, IM Rodríguez… - The American journal …, 2011 - journals.lww.com
Several classification schemes for penile precancerous lesions have been proposed, but
none of them seems to correlate with the current understanding of penile cancer …

Two major pathways of penile carcinogenesis: HPV-induced penile cancers overexpress p16ink4a, HPV-negative cancers associated with dermatoses express p53 …

S Mannweiler, S Sygulla, E Winter… - Journal of the American …, 2013 - Elsevier
BACKGROUND: Penile squamous cell carcinomas (SCC) arise either through transforming
infections with human papillomavirus (HPV) or independent of HPV, often in the background …

Distinctive association of p16INK4a overexpression with penile intraepithelial neoplasia depicting warty and/or basaloid features: a study of 141 cases evaluating a …

A Chaux, R Pfannl, B Lloveras, M Alejo… - The American journal …, 2010 - journals.lww.com
From the pathogenic point of view, penile cancers may be grouped in human papillomavirus-
related and unrelated tumors, each one of them with distinctive morphologic features. The …

Pathology of invasive and intraepithelial penile neoplasia

S Canete-Portillo, DF Sanchez, AL Cubilla - European Urology Focus, 2019 - Elsevier
Since 1995 it has been known that tumors harboring human papillomavirus (HPV)
preferentially show basaloid or condylomatous histological features, while HPV-negative …

[HTML][HTML] Human papillomavirus genotypes and P16INK4A expression in squamous penile carcinoma in Mexican patients

C Martínez-Bailón, A Mantilla-Morales… - BMC Infectious …, 2019 - Springer
Background Approximately 50% of cases of penile carcinoma (PeCa), a rare neoplasm
worldwide, are associated with human papillomavirus (HPV). However, the detection of HPV …