Advancing age leads to declines in physiological function and greatly increases risk for the
development of numerous diseases, including cardiovascular (CV), neurodegenerative, and …

The arterial system is integral to the proper function of all other organs and tissues. Arterial
function is impaired with aging, and arterial dysfunction contributes to the development of …

Key points Age‐related arterial dysfunction, characterized by oxidative stress‐and
inflammation‐mediated endothelial dysfunction and arterial stiffening, is the primary risk …

Results Conclusions Methods Acknowledgements Abstract Introduction Page 1 Young MA/O
0.0 0.5 1.0 1.5 2.0 2.5 C -re a c tiv e p ro te in (p g /m L ) * Young MA/O 0.0 0.1 0.2 0.3 0.4 0.5 P …

The gut microbiota is a critical regulator of human physiology, deleterious changes to its
composition and function (dysbiosis) have been linked to the development and progression …

Aging is associated with vascular endothelial dysfunction largely driven by reduced nitric
oxide (NO) bioavailability, which increases the risk of cardiovascular diseases (CVD) …

A growing body of evidence supports the concept that changes in microbiota composition in
ageing may be causally related to age-related changes in cardiovascular, immune …

Vascular dysfunction, characterized by arterial stiffness and endothelial dysfunction,
represents an important link between obesity and cardiovascular disease. Deleterious …

Vascular diseases, including atherosclerosis, aneurysms, and vascular calcification, are a
leading cause of morbidity and mortality worldwide. In past decades, the gut microbiota has …

Cardiovascular disease (CVD) is the leading cause of death worldwide. The human body is
populated by a diverse community of microbes, dominated by bacteria, but also including …