Honokiol: A review of its pharmacological potential and therapeutic insights

A Rauf, A Olatunde, M Imran, FA Alhumaydhi… - Phytomedicine, 2021 - Elsevier
Background Honokiol is a pleiotropic compound which been isolated from Magnolia species
such as Magnolia grandiflora and Magnolia dealbata. Magnolia species Magnolia …

Honokiol: a novel natural agent for cancer prevention and therapy

S Arora, S Singh, GA Piazza… - Current molecular …, 2012 - ingentaconnect.com
Honokiol (3', 5-di-(2-propenyl)-1, 1'-biphenyl-2, 4'-diol) is a bioactive natural product derived
from Magnolia spp. Recent studies have demonstrated anti-inflammatory, anti-angiogenic …

Honokiol for cancer therapeutics: A traditional medicine that can modulate multiple oncogenic targets

K Banik, AM Ranaware, V Deshpande… - Pharmacological …, 2019 - Elsevier
In spite of billions of dollars expended on cancer research every year, the incidence rate and
the mortality rate due to this widespread disease has increased drastically over the last few …

Honokiol: a review of its anticancer potential and mechanisms

CP Ong, WL Lee, YQ Tang, WH Yap - Cancers, 2019 - mdpi.com
Cancer is characterised by uncontrolled cell division and abnormal cell growth, which is
largely caused by a variety of gene mutations. There are continuous efforts being made to …

Honokiol, a multifunctional antiangiogenic and antitumor agent

LE Fried, JL Arbiser - Antioxidants & redox signaling, 2009 - liebertpub.com
Honokiol is a small-molecule polyphenol isolated from the genus Magnolia. It is
accompanied by other related polyphenols, including magnolol, with which it shares certain …

N europrotective effects of honokiol: from chemistry to medicine

S Talarek, J Listos, D Barreca, E Tellone, A Sureda… - Biofactors, 2017 - Wiley Online Library
The incidence of neurological disorders is growing in developed countries together with
increased lifespan. Nowadays, there are still no effective treatments for neurodegenerative …

Neuro-modulating effects of honokiol: a review

A Woodbury, SP Yu, L Wei, P García - Frontiers in neurology, 2013 - frontiersin.org
Honokiol is a poly-phenolic compound that exerts neuroprotective properties through a
variety of mechanisms. It has therapeutic potential in anxiety, pain, cerebrovascular injury …

Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer

H Liu, C Zang, A Emde, MD Planas-Silva… - European journal of …, 2008 - Elsevier
Honokiol, an active component isolated and purified from Chinese traditional herb magnolia,
was demonstrated to inhibit growth and induce apoptosis of different cancer cell lines such …

[HTML][HTML] Honokiol: An anticancer lignan

A Rauf, S Patel, M Imran, A Maalik, MU Arshad… - Biomedicine & …, 2018 - Elsevier
Abstract Background Honokiol ((3′, 5-di-(2-propenyl)-1, 1′-biphenyl-2, 2′-diol), a lignan,
is a promising antitumor compound, having exerted activity against a number of human …

Honokiol inhibits in vitro and in vivo growth of oral squamous cell carcinoma through induction of apoptosis, cell cycle arrest and autophagy

KJ Huang, CH Kuo, SH Chen, CY Lin… - Journal of Cellular and …, 2018 - Wiley Online Library
Honokiol, an active natural product derived from Magnolia officinalis, exerted anticancer
effects through a variety of mechanisms on multiple types of cancers. In this study, the …