Dysfunctional mitochondria as critical players in the inflammation of autoimmune diseases: Potential role in Sjögren's syndrome

MJ Barrera, S Aguilera, I Castro, P Carvajal, D Jara… - Autoimmunity …, 2021 - Elsevier
Relevant reviews highlight the association between dysfunctional mitochondria and
inflammation, but few studies address the contribution of mitochondria and mitochondria …

Mitochondrial oxidative stress and “mito-inflammation”: actors in the diseases

S Patergnani, E Bouhamida, S Leo, P Pinton… - Biomedicines, 2021 - mdpi.com
A decline in mitochondrial redox homeostasis has been associated with the development of
a wide range of inflammatory-related diseases. Continue discoveries demonstrate that …

Mitochondrial dysfunction and damage associated molecular patterns (DAMPs) in chronic inflammatory diseases

CSD Cruz, MJ Kang - Mitochondrion, 2018 - Elsevier
Inflammation represents a comprehensive host response to external stimuli for the purpose
of eliminating the offending agent, minimizing injury to host tissues and fostering repair of …

The mitochondrial associated endoplasmic reticulum membranes: A platform for the pathogenesis of inflammation‐mediated metabolic diseases

ST Degechisa, YT Dabi… - Immunity, Inflammation and …, 2022 - Wiley Online Library
Mitochondria‐associated endoplasmic reticulum membranes (MAM) are specialized
subcellular compartments that are shaped by endoplasmic reticulum (ER) subdomains …

The role of mitochondria in inflammation: from cancer to neurodegenerative disorders

S Missiroli, I Genovese, M Perrone, B Vezzani… - Journal of clinical …, 2020 - mdpi.com
The main features that are commonly attributed to mitochondria consist of the regulation of
cell proliferation, ATP generation, cell death and metabolism. However, recent scientific …

Mitochondrial dysfunction and oxidative stress in rheumatoid arthritis

MJ López-Armada, JA Fernández-Rodríguez… - Antioxidants, 2022 - mdpi.com
Control of excessive mitochondrial oxidative stress could provide new targets for both
preventive and therapeutic interventions in the treatment of chronic inflammation or any …

Mitochondria-associated membranes (MAMs) and inflammation

S Missiroli, S Patergnani, N Caroccia, G Pedriali… - Cell death & …, 2018 - nature.com
The endoplasmic reticulum (ER) and mitochondria are tightly associated with very dynamic
platforms termed mitochondria-associated membranes (MAMs). MAMs provide an excellent …

Mitochondrial control of inflammation

S Marchi, E Guilbaud, SWG Tait, T Yamazaki… - Nature Reviews …, 2023 - nature.com
Numerous mitochondrial constituents and metabolic products can function as damage-
associated molecular patterns (DAMPs) and promote inflammation when released into the …

Mitochondrial damage-associated molecular patterns: from inflammatory signaling to human diseases

S Grazioli, J Pugin - Frontiers in immunology, 2018 - frontiersin.org
Over the recent years, much has been unraveled about the pro-inflammatory properties of
various mitochondrial molecules once they are leaving the mitochondrial compartment. On …

Mitochondria, oxidative stress and innate immunity

Y Chen, Z Zhou, W Min - Frontiers in physiology, 2018 - frontiersin.org
Canonical functions of mitochondria include the regulation of cellular survival, orchestration
of anabolic and metabolic pathways, as well as reactive oxygen species (ROS) signaling …