OBJECTIVE: The associations of vitamin B12, folate, and homocysteine with depression
were examined in a population-based study. METHOD: The authors screened 3,884 elderly …

Background. Case control studies have supported a relationship between low folic acid and
vitamin B12 and high homocysteine levels as possible predictors of depression. The results …

OBJECTIVES: To investigate the independent associations between folate, B12, and
homocysteine levels and depressive symptoms in older adults. DESIGN: Cross‐sectional …

OBJECTIVE: It has been hypothesized that adequate concentrations of vitamin B12 and
folate are essential to maintain the integrity of the neurological systems involved in mood …

Objective: To examine, in a nationally representative sample of US adults, the associations
of serum folate, vitamin B-12, and total homocysteine (tHcy) levels with depressive …

Objective The authors examined the relationships between levels of three metabolites
(folate, vitamin B12, and homocysteine) and both depressive subtype and response to …

Homocysteine is a sensitive marker of folate and vitamin B12 deficiency. Numerous studies
have confirmed the association between folate deficiency and depression. It is not …

Background Depression is a heterogeneous disorder and is thought to develop as a result of
complex interactions between genetic and environmental factors. One‐carbon metabolism …

Background: Folate deficiency and low folate status have been linked in clinic studies to
depression, persistent depressive symptoms, and poor antidepressant response. These …

We review the findings in major depression of a low plasma and particularly red cell folate,
but also of low vitamin B12 status. Both low folate and low vitamin B12 status have been …