The amount of grafted poly (acrylic acid) on poly (methyl methacrylate) micro-and
nanoparticles was quantified by conductometry, 13C solid-state NMR, fluorophore labeling …

Surface-enhanced fluorescence has potentially many desirable properties as an analytical
method for medical diagnostics, but the effect observed so far is rather modest and only in …

We report a surface analytical study of poly (methyl methacrylate)(PMMA) microparticles
(beads) with a grafted shell of poly (acrylic acid)(PAA) with thicknesses up to 4 nm using …

Recently, numerous attempts have been made to improve the performance of fluorescence
immunoassays. One way pursued is the substitution of labeling molecules by micro-or …

Many applications of nanometer-and micrometer-sized particles include their surface
functionalization with linkers, sensor molecules, and analyte recognition moieties like (bio) …

Direct monitoring of recognition processes at the molecular level is a valuable tool for
studying reaction kinetics to assess affinity constants (eg drugs to receptors) and for …

Functional nanomaterials (NM) of different size, shape, chemical composition, and surface
chemistry are of increasing relevance for many key technologies of the twenty-first century …

Microbead-based assays have evolved into powerful tools for the multiplex detection of
biomolecules. Analytes are captured by DNA or protein capture molecules which are …

The surface modification of nanometer-and micrometer-sized particles and planar substrates
with polyethylene glycol (PEG) ligands of varying length is a very common strategy to tune …

In this article, we report on poly (amidoamine) dendrimers (PAMAM) as coupling agents for
recombinant single-chain (ScFv) antibodies to nanoparticle (NP) labels, for use in …