[图书][B] Polymeric micelles as a diagnostic tool for image-guided drug delivery and radiotherapy of HER2 overexpressing breast cancer

NB Hoang - 2014 - search.proquest.com
Block copolymer micelles have emerged as a viable formulation strategy with several drugs
relying on this technology in clinical evaluation. To date, information on the tumor …

Block copolymer micelles for delivery of cancer therapy: transport at the whole body, tissue and cellular levels

AS Mikhail, C Allen - Journal of Controlled Release, 2009 - Elsevier
The use of block copolymer micelles (BCMs) for the targeted delivery of chemotherapeutics
has proven to be a promising approach for improving the therapeutic efficacy of …

Block copolymer micelles as a solution for drug delivery problems

VP Torchilin - Expert opinion on therapeutic patents, 2005 - Taylor & Francis
Micelles, nanosized colloidal particles with a hydrophobic core and hydrophilic shell, can be
successfully used for the solubilisation of various poorly soluble pharmaceuticals, and …

The challenges facing block copolymer micelles for cancer therapy: in vivo barriers and clinical translation

S Eetezadi, SN Ekdawi, C Allen - Advanced drug delivery reviews, 2015 - Elsevier
The application of block copolymer micelles (BCMs) in oncology has benefitted from
advances in polymer chemistry, drug formulation and delivery as well as in vitro and in vivo …

Block copolymer micelles for drug delivery: design, characterization and biological significance

K Kataoka, A Harada, Y Nagasaki - Advanced drug delivery reviews, 2012 - Elsevier
Recently, colloidal carrier systems have been receiving much attention in the field of drug
targeting because of their high loading capacity for drugs as well as their unique disposition …

Roles of Passively and Actively Targeted Block Copolymer Micelles in Cancer Therapy

HHN Lee - 2010 - library-archives.canada.ca
Nanoparticle-based drug delivery systems (NDDS) have emerged as a promising strategy
for formulation of anticancer drugs due to their ability to passively target solid tumors via …

Overcoming the road blocks: advancement of block copolymer micelles for cancer therapy in the clinic

L Houdaihed, JC Evans, C Allen - Molecular pharmaceutics, 2017 - ACS Publications
With countless preclinical studies on block copolymer micelles (BCMs) successfully
demonstrating the superiority of these advanced drug delivery formulations over …

[HTML][HTML] Polymeric micelles in anticancer therapy: targeting, imaging and triggered release

C Oerlemans, W Bult, M Bos, G Storm… - Pharmaceutical …, 2010 - Springer
Micelles are colloidal particles with a size around 5–100 nm which are currently under
investigation as carriers for hydrophobic drugs in anticancer therapy. Currently, five micellar …

In Vivo Distribution of Polymeric Nanoparticles at the Whole-Body, Tumor, and Cellular Levels

H Lee, B Hoang, H Fonge, RM Reilly, C Allen - Pharmaceutical research, 2010 - Springer
Abstract Purpose Block copolymer micelles (BCMs) were functionalized with indium-111
and/or epidermal growth factor (EGF), which enabled investigation of the in vivo transport of …

Docetaxel-loaded block copolymer micelles labeled with 188Re for combined radiochemotherapy

E Ribeiro, F Marques, L Gano, JDG Correia… - Journal of Drug Delivery …, 2020 - Elsevier
Block copolymer micelles (BCMs), nano-self-assemblies of amphiphilic copolymers with a
hydrophobic core surrounded by a hydrophilic corona, were explored for the simultaneous …