Molecular features encoded in the ctDNA reveal heterogeneity and predict outcome in high-risk aggressive B-cell lymphoma
L Meriranta, A Alkodsi, A Pasanen… - Blood, The Journal …, 2022 - ashpublications.org
Inadequate molecular and clinical stratification of the patients with high-risk diffuse large B-
cell lymphoma (DLBCL) is a clinical challenge hampering the establishment of personalized …
cell lymphoma (DLBCL) is a clinical challenge hampering the establishment of personalized …
Diffuse large B-cell lymphoma genotyping on the liquid biopsy
D Rossi, F Diop, E Spaccarotella… - Blood, The Journal …, 2017 - ashpublications.org
Accessible and real-time genotyping for diagnostic, prognostic, or treatment purposes is
increasingly impelling in diffuse large B-cell lymphoma (DLBCL). Cell-free DNA (cfDNA) is …
increasingly impelling in diffuse large B-cell lymphoma (DLBCL). Cell-free DNA (cfDNA) is …
Non-invasive monitoring of diffuse large B-cell lymphoma by cell-free DNA high-throughput targeted sequencing: analysis of a prospective cohort
E Bohers, PJ Viailly, S Becker, V Marchand… - Blood cancer …, 2018 - nature.com
From a liquid biopsy, cell-free DNA (cfDNA) can provide information regarding basal tumoral
genetic patterns and changes upon treatment. In a prospective cohort of 30 diffuse large B …
genetic patterns and changes upon treatment. In a prospective cohort of 30 diffuse large B …
Distinct biological subtypes and patterns of genome evolution in lymphoma revealed by circulating tumor DNA
Patients with diffuse large B cell lymphoma (DLBCL) exhibit marked diversity in tumor
behavior and outcomes, yet the identification of poor-risk groups remains challenging. In …
behavior and outcomes, yet the identification of poor-risk groups remains challenging. In …
Mutational landscape and tumor burden assessed by cell-free DNA in diffuse large B-cell lymphoma in a population-based study
A Rivas-Delgado, F Nadeu, A Enjuanes… - Clinical Cancer …, 2021 - AACR
Purpose: We analyzed the utility of cell-free DNA (cfDNA) in a prospective population-based
cohort to determine the mutational profile, assess tumor burden, and estimate its impact in …
cohort to determine the mutational profile, assess tumor burden, and estimate its impact in …
Whole-exome analysis reveals novel somatic genomic alterations associated with outcome in immunochemotherapy-treated diffuse large B-cell lymphoma
Lack of remission or early relapse remains a major clinical issue in diffuse large B-cell
lymphoma (DLBCL), with 30% of patients failing standard of care. Although clinical factors …
lymphoma (DLBCL), with 30% of patients failing standard of care. Although clinical factors …
Molecular determinants of clinical outcomes in a real-world diffuse large B-cell lymphoma population
W Alduaij, B Collinge, S Ben-Neriah… - Blood, The Journal …, 2023 - ashpublications.org
Molecular heterogeneity of diffuse large B-cell lymphoma (DLBCL) underlies the variable
outcomes achieved with immunochemotherapy. However, outcomes of gene expression …
outcomes achieved with immunochemotherapy. However, outcomes of gene expression …
Liquid biopsy in lymphoma: Molecular methods and clinical applications
M Cirillo, AFM Craig, S Borchmann, DM Kurtz - Cancer treatment reviews, 2020 - Elsevier
In this article, we broadly review the application of cfDNA analysis to the diagnosis and
management of lymphoma. We introduce the advantages of cfDNA measurement over …
management of lymphoma. We introduce the advantages of cfDNA measurement over …
Molecular classification of mature aggressive B-cell lymphoma using digital multiplexed gene expression on formalin-fixed paraffin-embedded biopsy specimens
N Masqué-Soler, M Szczepanowski… - Blood, The Journal …, 2013 - ashpublications.org
The most frequent mature aggressive B-cell lymphomas are diffuse large B-cell lymphoma
(DLBCL) and Burkitt lymphoma (BL). Patients suffering from molecularly defined BL (mBL) …
(DLBCL) and Burkitt lymphoma (BL). Patients suffering from molecularly defined BL (mBL) …
[HTML][HTML] Circulating tumor DNA measurements as early outcome predictors in diffuse large B-cell lymphoma
Purpose Outcomes for patients with diffuse large B-cell lymphoma remain heterogeneous,
with existing methods failing to consistently predict treatment failure. We examined the …
with existing methods failing to consistently predict treatment failure. We examined the …